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从 亚种中分离得到的一种新型二聚类黄酮糖苷。

A novel dimeric flavonol glycoside from subsp. .

机构信息

a Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, School of Pharmacy, Ministry of Education , Shihezi University , Shihezi , P.R. China.

b School of Pharmacy, Department of Pharmacognosy , Fudan University , Shanghai , P.R. China.

出版信息

Nat Prod Res. 2019 Jul;33(14):2032-2037. doi: 10.1080/14786419.2018.1483931. Epub 2018 Jun 11.

DOI:10.1080/14786419.2018.1483931
PMID:29890861
Abstract

A novel dimeric flavonol glycoside, Cynanflavoside A (), together with six analogues, kaempferol-3---L-rhamnopyranosyl-(1→2)--D-glucopyranoside (), quercetin-3---L-rhamnopyranosyl-(1→2)--D-glucopyranoside (), kaempferol-3---L-rhamnopyranosyl-(1→2)--D-xylopyranoside (), quercetin-3---L-rhamnopyranosyl-(1→2)--D-xylopyranoside , kaempferol-3---D-glucopyranosyl-7---L-rhamnopyranoside (), and quercetin-3--galactoside () were isolated from the -butyl alcohol extract of subsp. . Their structures were determined spectroscopically and compared with previously reported spectral data. All compounds were evaluated for their anti-complementary activity , and only compound exhibited anti-complement effects with CH value of 0.33 mM.

摘要

从 subsp. 的正丁醇提取物中分离得到一种新的二聚类黄酮糖苷 Cynanflavoside A (),以及 6 种类似物:kaempferol-3---L-rhamnopyranosyl-(1→2)--D-glucopyranoside ()、quercetin-3---L-rhamnopyranosyl-(1→2)--D-glucopyranoside ()、kaempferol-3---L-rhamnopyranosyl-(1→2)--D-xylopyranoside ()、quercetin-3---L-rhamnopyranosyl-(1→2)--D-xylopyranoside ()、kaempferol-3---D-glucopyranosyl-7---L-rhamnopyranoside ()和 quercetin-3--galactoside ()。它们的结构通过光谱法确定,并与以前报道的光谱数据进行了比较。所有化合物均进行了抗补体活性评估,只有化合物 表现出抗补体作用,CH 值为 0.33 mM。

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