Ebtekar Fariba, Dalvand Sahar, Gheshlagh Reza Ghanei
Dept. of Midwifery, Faculty of Nursing and Midwifery, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Clinical Care Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Diabetes Metab Syndr. 2018 Nov;12(6):955-960. doi: 10.1016/j.dsx.2018.06.002. Epub 2018 Jun 6.
Metabolic syndrome is a set of cardiovascular risk factors that increase the risk of cardiovascular disease, diabetes and mortality. Women are at risk of developing metabolic syndrome as they enter the postmenopausal period. The present systematic review and meta-analysis was conducted to estimate the prevalence of metabolic syndrome in Iranian postmenopausal women. In this systematic review and meta-analysis, 16 national articles published in Persian and English were gathered without time limit. National databases such as SIDs, IranMedex and MagIran, and international databases such as Web of Science, Google Scholar, PubMed and Scopus were used to search the relevant studies. We searched for articles using the keywords "menopause", "postmenopausal", "metabolic syndrome", "MetSyn", and their combinations. Data were analyzed using the meta-analysis method and the random effects model. Analysis of 16 selected articles with a sample size of 5893 people showed that the prevalence of metabolic syndrome in Iranian postmenopausal women was 51.6% (95% CI: 43-60). The prevalence of metabolic syndrome based on ATP III and IDF criteria was 54% (95% CI: 59-63) and 50% (95% CI: 45-56), respectively. Based on the results of univariate meta-regression analysis, the increase in the mean age of postmenopausal women (p = 0.001) and sample size (p = 0.029), the prevalence of metabolic syndrome increased significantly. More than half of postmenopausal women in Iran suffer from metabolic syndrome. Providing training programs for postmenopausal women to prevent and control cardiovascular disease and its complications seems to be necessary.
代谢综合征是一组心血管危险因素，会增加患心血管疾病、糖尿病和死亡的风险。女性进入绝经后期有患代谢综合征的风险。本系统评价和荟萃分析旨在估计伊朗绝经后女性代谢综合征的患病率。在这项系统评价和荟萃分析中，不限时间收集了16篇用波斯语和英语发表的国内文章。使用SID、IranMedex和MagIran等国内数据库以及Web of Science、谷歌学术、PubMed和Scopus等国际数据库来检索相关研究。我们使用关键词“绝经”“绝经后”“代谢综合征”“MetSyn”及其组合来搜索文章。采用荟萃分析方法和随机效应模型进行数据分析。对16篇选定文章进行分析，样本量为5893人，结果显示伊朗绝经后女性代谢综合征的患病率为51.6%（95%置信区间：43 - 60）。基于ATP III和IDF标准的代谢综合征患病率分别为54%（95%置信区间：59 - 63）和50%（95%置信区间：45 - 56）。基于单变量荟萃回归分析结果，绝经后女性平均年龄的增加（p = 0.001）和样本量的增加（p = 0.029），代谢综合征的患病率显著增加。伊朗超过一半的绝经后女性患有代谢综合征。为绝经后女性提供预防和控制心血管疾病及其并发症的培训项目似乎很有必要。
