老年人代谢综合征的性别特异性患病率：伊朗内沙布尔衰老纵向研究结果
Sex-specific prevalence of metabolic syndrome in older adults: results from the Neyshabur longitudinal study on aging, Iran.
作者信息
Azimi-Nezhad Mohsen, Aminisani Nayyereh, Ghasemi Ahmad, Farimani Azam Rezaei, Khorashadizadeh Fatemeh, Mirhafez Seyed Reza, Hyde Martin, Shamshirgaran Seyed Morteza
机构信息
Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, 9329774448 Neyshabur, Iran.
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
出版信息
J Diabetes Metab Disord. 2022 Jan 17;21(1):263-273. doi: 10.1007/s40200-022-00969-6. eCollection 2022 Jun.
PURPOSE
The prevalence of metabolic syndrome (MetS) and associated diseases grows as the population ages. This study aimed to investigate sex differences in the prevalence of MetS and its components among people aged 50 years and older in Iran.
METHODS
Data were drawn from the Neyshabur Longitudinal Study on Ageing (NeLSA), which is an ageing component of the Prospective Epidemiological Research Studies in IraAn (PERSIAN). The NCEP ATP III and IDF criteria were used to identify the prevalence of MetS among 3383 men and 3873 women aged 50 years and older. Sociodemographic information, lifestyle and clinical factors were collected via an interview-based questionnaire. Weight and height, waist circumferences and blood pressure were measured. Laboratory measures such as fasting blood sugar, triglycerides and high-density cholesterol were also assessed.
RESULTS
The overall prevalence of the MetS according to the NCEP ATP III and IDF definitions were 45% and 47%, respectively. The prevalence of the MetS in men and women was 37% and 63% according to the NCEP ATP III definition, 33% and 67% by the IDF definition, respectively The prevalence of MetS components was significantly higher in women than in men.
CONCLUSION
In the current study, the prevalence of MetS and its components was significantly higher among women than men. We also observed good concordance between IDF and NCEP ATP III criteria.
目的
随着人口老龄化，代谢综合征（MetS）及相关疾病的患病率不断上升。本研究旨在调查伊朗50岁及以上人群中MetS及其组成成分的患病率的性别差异。
方法
数据取自内沙布尔老龄化纵向研究（NeLSA），该研究是伊朗前瞻性流行病学研究（PERSIAN）的老龄化组成部分。采用美国国家胆固醇教育计划成人治疗组第三次报告（NCEP ATP III）和国际糖尿病联盟（IDF）标准，确定3383名50岁及以上男性和3873名50岁及以上女性中MetS的患病率。通过基于访谈的问卷收集社会人口学信息、生活方式和临床因素。测量体重、身高、腰围和血压。还评估了空腹血糖、甘油三酯和高密度胆固醇等实验室指标。
结果
根据NCEP ATP III和IDF定义，MetS的总体患病率分别为45%和47%。根据NCEP ATP III定义，男性和女性中MetS的患病率分别为37%和63%，根据IDF定义分别为33%和67%。MetS各组成成分的患病率在女性中显著高于男性。
结论
在本研究中，MetS及其组成成分的患病率在女性中显著高于男性。我们还观察到IDF和NCEP ATP III标准之间具有良好的一致性。
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