Arbabi Mohammad, Shahhatami Fatemeh, Mojtahedzadeh Mojtaba, Mohammadi Mostafa, Ghaeli Padideh
Neuropsychiatry Section of Iranian Psychiatric Association, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Psychiatry. 2018 Jan;13(1):65-79.
Delirium is a brain dysfunction syndrome. In most cases, this syndrome is neither diagnosed accurately nor treated properly. The incidence of delirium by itself increases hospitalization period, mortality rate and the cost in health spectrum. If appropriate attempts are not made to treat this complication, the outcomes could become worse. Thus, the present study aimed at conducting a review on medications which are prescribed to treat delirium and establishing a general view on their advantages and disadvantages. By searching Google Scholar, PsycINFO, Scopus, and PubMed databases as well as hand searching in key journals, data were collected without time and language limitation. After collecting the data, comparing the similar or contradictory information, and sorting them, the views of specialists were inquired and duly received via email. By acquiring consensus of opinions, the secondary manuscript was written in a narrative review form. This narrative review paper aimed at providing a general view on defining delirium, the pathologic factors that create it, and treating this syndrome based on its development. Authentic evidence regarding delirium management was reviewed and a treatment strategy was suggested for Iranian patients.
谵妄是一种脑功能障碍综合征。在大多数情况下，这种综合征既未得到准确诊断，也未得到恰当治疗。谵妄本身的发生率会延长住院时间、增加死亡率以及医疗费用。如果不采取适当措施治疗这种并发症，后果可能会更糟。因此，本研究旨在对用于治疗谵妄的药物进行综述，并对其优缺点形成总体认识。通过搜索谷歌学术、心理学文摘数据库、Scopus数据库和PubMed数据库，以及在主要期刊中进行手工检索，不限时间和语言收集数据。收集数据、比较相似或矛盾的信息并进行整理后，通过电子邮件咨询并适时收到了专家的意见。通过达成意见共识，以叙述性综述的形式撰写了第二篇手稿。这篇叙述性综述文章旨在对谵妄的定义、引发谵妄的病理因素以及根据其发展过程治疗该综合征提供总体认识。对有关谵妄管理的可靠证据进行了综述，并为伊朗患者提出了一种治疗策略。
