a Islamic Azad University , Karaj , Iran.
b Psychiatric Clinics (UPK), Center for Affective, Stress and Sleep Disorders (ZASS) , University of Basel , Basel , Switzerland.
Cogn Behav Ther. 2018 Sep;47(5):431-446. doi: 10.1080/16506073.2018.1445773. Epub 2018 Jun 12.
Even 30 or more years after the end of a war, veterans can suffer from post-traumatic stress disorder (PTSD). In the present study, we explored the influence on symptoms of PTSD among Iranian veterans of the Iran-Iraq war of mindfulness-based cognitive therapy (MBCT) as add-on to a standard treatment with citalopram. Forty-eight male veterans with PTSD (mean age: 52.97 years) took part in this eight-week intervention study. Standard treatment for all patients consisted of citalopram (30-50 mg/day at therapeutic dosages). Patients were randomly assigned either to the treatment or to the control condition. Treatment involved MBCT delivered in group sessions once a week. Patients in the control condition met at the hospital with the same frequency and duration for socio-therapeutic events. At baseline and at study completion, patients completed questionnaires covering symptoms of PTSD, depression, anxiety, and stress. At study completion after eight weeks, scores for PTSD (re-experiencing events, avoidance, negative mood and cognition, hyperarousal), depression, anxiety, and stress were lower, but more so in the intervention than the control group. Data suggest that, as adjuvant to standard SSRI medication, MBCT is an effective intervention to significantly reduce symptoms of PTSD, depression, anxiety, and stress among veterans.
即使在战争结束 30 年或更长时间后,退伍军人仍可能患有创伤后应激障碍(PTSD)。在本研究中,我们探讨了正念认知疗法(MBCT)对伊朗-伊拉克战争退伍军人 PTSD 症状的影响,MBCT 是作为西酞普兰标准治疗的附加治疗。48 名患有 PTSD 的男性退伍军人(平均年龄:52.97 岁)参加了这项为期八周的干预研究。所有患者的标准治疗均包括西酞普兰(治疗剂量为 30-50mg/天)。患者被随机分配到治疗组或对照组。治疗包括每周一次的小组正念认知疗法。对照组患者以相同的频率和持续时间在医院参加社会治疗活动。在基线和研究完成时,患者完成了涵盖 PTSD、抑郁、焦虑和压力症状的问卷。在八周后的研究完成时,PTSD(重新体验事件、回避、负面情绪和认知、过度警觉)、抑郁、焦虑和压力的评分较低,但干预组的评分比对照组更低。数据表明,作为 SSRI 药物标准治疗的辅助手段,MBCT 是一种有效的干预措施,可显著减轻退伍军人 PTSD、抑郁、焦虑和压力的症状。