Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA.
Depress Anxiety. 2013 Jul;30(7):638-45. doi: 10.1002/da.22104. Epub 2013 Apr 17.
"Mindfulness-based" interventions show promise for stress reduction in general medical conditions, and initial evidence suggests that they are accepted in trauma-exposed individuals. Mindfulness-based cognitive therapy (MBCT) shows substantial efficacy for prevention of depression relapse, but it has been less studied in anxiety disorders. This study investigated the feasibility, acceptability, and clinical outcomes of an MBCT group intervention adapted for combat posttraumatic stress disorder (PTSD).
Consecutive patients seeking treatment for chronic PTSD at a VA outpatient clinic were enrolled in 8-week MBCT groups, modified for PTSD (four groups, n = 20) or brief treatment-as-usual (TAU) comparison group interventions (three groups, n = 17). Pre and posttherapy psychological assessments with clinician administered PTSD scale (CAPS) were performed with all patients, and self-report measures (PTSD diagnostic scale, PDS, and posttraumatic cognitions inventory, PTCI) were administered in the MBCT group.
Intent to treat analyses showed significant improvement in PTSD (CAPS (t(19) = 4.8, P < .001)) in the MBCT condition but not the TAU conditions, and a significant Condition × Time interaction (F[1,35] = 16.4, P < .005). MBCT completers (n = 15, 75%) showed good compliance with assigned homework exercises, and significant and clinically meaningful improvement in PTSD symptom severity on posttreatment assessment in CAPS and PDS (particularly in avoidance/numbing symptoms), and reduced PTSD-relevant cognitions in PTCI (self blame).
These data suggest group MBCT as an acceptable brief intervention/adjunctive therapy for combat PTSD, with potential for reducing avoidance symptom cluster and PTSD cognitions. Further studies are needed to examine efficacy in a randomized controlled design and to identify factors influencing acceptability and efficacy.
“正念为基础”的干预措施在一般医疗条件下显示出减轻压力的潜力,初步证据表明,它们在经历过创伤的个体中是可以被接受的。正念认知疗法(MBCT)在预防抑郁症复发方面显示出显著的疗效,但在焦虑症中研究较少。本研究调查了适应创伤后应激障碍(PTSD)的基于正念的认知疗法(MBCT)团体干预的可行性、可接受性和临床结果。
连续就诊于退伍军人事务部门诊的慢性 PTSD 患者被纳入 8 周的 MBCT 团体,分为 PTSD 修正组(四组,n=20)和简短治疗常规组(三组,n=17)。所有患者均接受了治疗前和治疗后的心理评估,包括临床医生管理的 PTSD 量表(CAPS)和自我报告的量表(PTSD 诊断量表、PDS 和创伤后认知量表、PTCI)。
意向治疗分析显示,MBCT 条件下 PTSD(CAPS(t(19)=4.8,P<.001))显著改善,但 TAU 条件下没有改善,并且存在条件与时间的显著交互作用(F[1,35]=16.4,P<.005)。MBCT 完成者(n=15,75%)很好地完成了指定的家庭作业,CAPS 和 PDS 的 PTSD 症状严重程度在治疗后评估中显著改善,具有临床意义(特别是回避/麻木症状),PTCI 中的 PTSD 相关认知(自责)减少。
这些数据表明,MBCT 团体疗法是一种可以接受的治疗战斗 PTSD 的简短干预/辅助疗法,具有减少回避症状群和 PTSD 认知的潜力。需要进一步的研究来检验随机对照设计中的疗效,并确定影响可接受性和疗效的因素。