Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA, USA.
Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong Special Administrative Region, China.
Lancet Oncol. 2018 Jun;19(6):e305-e316. doi: 10.1016/S1470-2045(18)30348-6. Epub 2018 Jun 1.
As the worldwide population ages, oncologists are often required to make difficult and complex decisions regarding the treatment of older people (aged 65 years and older) with cancer. Chronological age alone is often a poor indicator of the physiological and functional status of older adults, and thus should not be the main factor guiding treatment decisions in oncology. By contrast, a geriatric assessment can provide a much more comprehensive understanding of the functional and physiological age of an older person with cancer. The geriatric assessment is a multidimensional tool that evaluates several domains, including physical function, cognition, nutrition, comorbidities, psychological status, and social support. In this Series paper, we discuss the use of a geriatric assessment-based approach to cancer care, and provide clinicians with tools to better assess the risks and benefits of treatment to engage in shared decision making and provide better personalised care for older people with cancer.
随着全球人口老龄化，肿瘤学家经常需要就癌症老年患者（65 岁及以上）的治疗做出困难和复杂的决策。单纯的年龄并不能很好地反映老年人的生理和功能状态，因此不应该成为肿瘤学治疗决策的主要因素。相比之下，老年综合评估可以更全面地了解癌症老年患者的功能和生理年龄。老年综合评估是一种多维工具，可评估多个领域，包括身体功能、认知、营养、合并症、心理状态和社会支持。在本系列论文中，我们讨论了基于老年综合评估的方法在癌症治疗中的应用，并为临床医生提供了工具，以更好地评估治疗的风险和益处，从而进行共同决策，并为癌症老年患者提供更好的个性化护理。
