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伴有转移的鼻窦恶性黑色素瘤:免疫组织化学应对诊断挑战

Sinonasal malignant melanoma with metastasis: Immunohistochemistry meeting the diagnostic challenge.

作者信息

Gupta Prajwala, Bhardwaj Minakshi

机构信息

Department of Pathology, Post Graduate Institute of Medical Education and Research and Dr. RML Hospital, New Delhi, India.

出版信息

J Cancer Res Ther. 2018 Apr-Jun;14(3):709-711. doi: 10.4103/0973-1482.180612.

Abstract

Sinonasal malignant melanoma is one of the uncommon and highly aggressive tumors of the sinonasal cavity. Cytomorphological features in a metastatic lymph node may reveal a diagnosis of malignant melanoma. This case had nondiagnostic cytological and histopathological features, which could suggest malignant melanoma. Immunohistochemistry in such cases becomes the primary method for establishing the diagnosis of malignant melanoma at an uncommon site.

摘要

鼻窦恶性黑色素瘤是鼻窦腔罕见且侵袭性很强的肿瘤之一。转移淋巴结的细胞形态学特征可能提示恶性黑色素瘤的诊断。该病例的细胞学和组织病理学特征不具有诊断性,可能提示恶性黑色素瘤。在这种情况下,免疫组织化学成为在不常见部位确立恶性黑色素瘤诊断的主要方法。

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