Koo Ho Seok, Hong Soo Min
Department of Internal Medicine, Seoul Paik Hospital, College of Medicine, Inje University , Seoul, South Korea .
Metab Syndr Relat Disord. 2018 Sep;16(7):375-381. doi: 10.1089/met.2018.0003. Epub 2018 Jun 12.
The incidence of periodontitis is higher when metabolic syndrome (MS) is present. However, only few Korean studies have compared the risk factors for MS and periodontitis. Therefore, this study aimed to investigate the prevalence and risk factors for periodontitis relative to the presence of MS.
The data collected from 13,196 respondents of the 2010-2015 Korea National Health and Nutrition Examination Survey in South Korea, which include periodontitis and MS parameters, were analyzed after propensity score matching of sex and age.
A total of 29% of the participants had periodontitis. The periodontitis group had more males (53%), lower number of participants who had a high educational level (66.6%), and higher body mass index (24.3 ± 3.2) and waist circumference (83.8 ± 9.2) than the nonperiodontitis group. Moreover, the periodontitis group exhibited higher systolic blood pressure and fasting plasma glucose and plasma triglyceride levels, but lower high-density lipoprotein cholesterol levels than the nonperiodontitis group (P < 0.001). Several patients in the periodontitis group had hypertension (43.3%) and diabetes mellitus (17.3%), but only few had chronic kidney disease (3.4%). Multiple regression analysis showed that the risk of periodontitis increased when MS, diabetes mellitus, and smoking history were present. Particularly, the risk of periodontitis increased as the number of MS components increased (P < 0.001).
Patients with MS had 1.12-fold higher risk of periodontitis than those without. Additionally, patients who had diabetes mellitus and were smokers had a particularly high risk of periodontitis. The risk of periodontitis increased as the number of MS components increased.
存在代谢综合征（MS）时，牙周炎的发病率更高。然而，韩国仅有少数研究比较了MS和牙周炎的危险因素。因此，本研究旨在调查相对于MS的存在而言，牙周炎的患病率及危险因素。
对2010 - 2015年韩国国民健康与营养检查调查中13196名受访者收集的数据进行分析，这些数据包括牙周炎和MS参数，在按性别和年龄进行倾向得分匹配后进行分析。
共有29%的参与者患有牙周炎。牙周炎组男性更多（53%），受教育程度高的参与者数量更少（66.6%），且体重指数（24.3±3.2）和腰围（83.8±9.2）高于非牙周炎组。此外，与非牙周炎组相比，牙周炎组收缩压、空腹血糖和血浆甘油三酯水平更高，但高密度脂蛋白胆固醇水平更低（P<0.001）。牙周炎组的一些患者患有高血压（43.3%）和糖尿病（17.3%），但只有少数患有慢性肾病（3.4%）。多元回归分析显示，存在MS、糖尿病和吸烟史时，牙周炎风险增加。特别是，牙周炎风险随着MS组分数量的增加而增加（P<0.001）。
患有MS的患者患牙周炎的风险比未患MS的患者高1.12倍。此外，患有糖尿病且吸烟的患者患牙周炎的风险特别高。牙周炎风险随着MS组分数量的增加而增加。
