Kim Si-Wan, Cho Kyung-Hwan, Han Kyung-Do, Roh Yong-Kyun, Song In-Seok, Kim Yang-Hyun
From the Department of Family Medicine, Ree and Jang Plastic Surgery Clinic (SWK, YHK); Department of Family Medicine, Korea University College of Medicine (KHC); Department of Medical Statistics, Catholic University College of Medicine (KDH); Department of Family Medicine, Hallym University College of Medicine (YKR); and Department of Dentistry, Korea University College of Medicine (ISS), Seoul, South Korea.
Medicine (Baltimore). 2016 Apr;95(16):e3331. doi: 10.1097/MD.0000000000003331.
To evaluate the relationship between tooth loss and metabolic syndrome (MS) in South Korean adults.
A total of 3589 adults (1511 men and 2078 women aged over 40 years) from the 2012 Korean National Health and Nutrition Examination Survey were included and divided into 3 groups according to the number of remaining teeth (0-19, 20-27, and 28). We recorded the number of remaining teeth and measured MS components such as waist circumference, systolic and diastolic blood pressure, fasting blood glucose, serum high-density lipoprotein-cholesterol, and triglyceride concentration. We also calculated the number of subjects who met the inclusion criteria of MS in each group. Multiple logistic regression analysis was performed to estimate the prevalence of MS components according to the number of remaining teeth after adjusting for covariates. Women without MS had significantly more teeth than those with MS (24.5 ± 0.2 vs 21.0 ± 0.3). In men, the prevalence of high blood pressure and high fasting blood glucose levels were significantly different among the 3 groups (P = 0.003 and P < 0.001, respectively); however, the prevalence of MS and all MS components were significantly different in women (P < 0.001 for all comparisons). Men with 0 to 19 remaining teeth were most likely to have high blood pressure and high fasting blood glucose, while women with 0 to 19 remaining teeth had the highest prevalence of MS and each MS component. Multiple logistic regression analysis revealed that women with fewer remaining teeth had a higher prevalence of MS and MS components after adjusting for covariates. Having only a few remaining teeth was associated with MS in women in South Korea.
评估韩国成年人牙齿缺失与代谢综合征（MS）之间的关系。
纳入2012年韩国国民健康与营养检查调查中的3589名成年人（1511名男性和2078名40岁以上女性），并根据剩余牙齿数量分为3组（0 - 19颗、20 - 27颗和28颗）。我们记录了剩余牙齿数量，并测量了MS的各项指标，如腰围、收缩压和舒张压、空腹血糖、血清高密度脂蛋白胆固醇以及甘油三酯浓度。我们还计算了每组中符合MS纳入标准的受试者数量。进行多因素逻辑回归分析，以在调整协变量后根据剩余牙齿数量估计MS各项指标的患病率。无MS的女性比患有MS的女性牙齿明显更多（24.5 ± 0.2 vs 21.0 ± 0.3）。在男性中，3组之间高血压和高空腹血糖水平的患病率有显著差异（分别为P = 0.003和P < 0.001）；然而，女性中MS及所有MS指标的患病率有显著差异（所有比较P < 0.001）。剩余牙齿为0至19颗的男性最有可能患有高血压和高空腹血糖，而剩余牙齿为0至19颗的女性MS及各MS指标的患病率最高。多因素逻辑回归分析显示，在调整协变量后，剩余牙齿较少的女性MS及MS指标的患病率更高。在韩国女性中，剩余牙齿较少与MS有关。
