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基于皮肤癌类型、尺寸和位置的莫氏手术一期缝合长度预测模型。

A Predictive Model for Primary Closure Lengths in Mohs Surgery Based on Skin Cancer Type, Dimensions, and Location.

作者信息

Theroux Zachary A, Blechman Adam B, Russell Mark A

机构信息

Department of Dermatology, University of Virginia Health System, Charlottesville, Virginia.

The Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.

出版信息

Dermatol Surg. 2019 Jan;45(1):36-43. doi: 10.1097/DSS.0000000000001571.

Abstract

BACKGROUND

Surgical scar length is a common concern among patients undergoing Mohs micrographic surgery (MMS).

OBJECTIVE

This study evaluates 3 metrics of preoperative lesion size to determine which correlates best with primary linear closure lengths for nonmelanoma skin cancers (NMSCs) treated with MMS. This metric is then used to develop predictive models for linear closure lengths in 10 different anatomical regions.

MATERIALS AND METHODS

A retrospective study of 4,049 NMSCs treated with MMS and repaired with primary linear closure was conducted. Primary closure lengths were plotted against preoperative lesion circumference, area, and short axis length. Linear regression analysis was performed.

RESULTS

Preoperative NMSC circumference correlated best with closure length. Twenty-one of the 28 regression models had coefficients of determination (R) above 0.5. Closure lengths increased by 0.52 to 1.1 mm, depending on location, for every millimeter increase in preoperative NMSC circumference.

CONCLUSION

Preoperative lesion circumference is directly proportional to primary closure length and is a better indicator of closure length than preoperative area and short axis for MMS of NMSCs. Closure lengths located on the nasal tip, supratip, or periocular areas are most sensitive to differences in NMSC size. These data might aid Mohs surgeons with preoperative planning for wound reconstruction and patient counseling.

摘要

背景

手术瘢痕长度是接受莫氏显微外科手术(MMS)的患者普遍关注的问题。

目的

本研究评估术前病损大小的三个指标,以确定哪个指标与接受MMS治疗的非黑素瘤皮肤癌(NMSC)的一期线性缝合长度相关性最佳。然后使用该指标建立10个不同解剖区域线性缝合长度的预测模型。

材料与方法

对4049例接受MMS治疗并采用一期线性缝合修复的NMSC进行回顾性研究。将一期缝合长度与术前病损周长、面积和短轴长度进行绘图。进行线性回归分析。

结果

术前NMSC周长与缝合长度相关性最佳。28个回归模型中有21个的决定系数(R)高于0.5。术前NMSC周长每增加1毫米,缝合长度根据位置增加0.52至1.1毫米。

结论

术前病损周长与一期缝合长度成正比,对于NMSC的MMS,它比术前面积和短轴更能准确预测缝合长度。鼻尖、鼻尖上方或眼周区域的缝合长度对NMSC大小差异最为敏感。这些数据可能有助于莫氏外科医生进行伤口重建的术前规划和患者咨询。

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