Martínez Pascual Paula, Amaro Merino Pedro
Servicio de Otorrinolaringología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Instituto Otovértigo, Madrid, España.
Acta Otorrinolaringol Esp (Engl Ed). 2019 May-Jun;70(3):131-135. doi: 10.1016/j.otorri.2018.04.003. Epub 2018 Jun 9.
Benign paroxysmal positional vertigo (BPPV) pathophysiology is based on otoconia migration from the utricle and saccule to the semicircular canals, however, the role of the saccule is still under study. Our aim is to study the otolith damage in these patients with vestibular evoked myogenic potentials (VEMPS) and correlate the results with those of computerised dynamic posturography (CDP).
We present 79 patients diagnosed with BPPV between March and June 2017. VEMPS and CDP studies were performed. We selected 67 patients with posterior semi-circular canal BPPV and we compared them with 60 healthy subjects.
BPPV group had abnormal cervical VEMPS in 49.25% of patients compared to 16.67% in the control group. Ocular VEMPS were altered in 61.19% of the patients and 6.67% of the healthy subjects. Abnormal ocular VEMPS in patients with recurrent BPPV was statistically significant. There was no significant correlation with CDP results.
Utricular and saccular dysfunction in BPPV patients proved by VEMPS is higher than in healthy individuals. This result may be related to symptoms of instability experienced by these patients occasionally.
良性阵发性位置性眩晕（BPPV）的病理生理学基于耳石从椭圆囊和球囊迁移至半规管，然而，球囊的作用仍在研究中。我们的目的是通过前庭诱发肌源性电位（VEMPs）研究这些患者的耳石损伤，并将结果与计算机动态姿势描记法（CDP）的结果进行关联。
我们纳入了2017年3月至6月间诊断为BPPV的79例患者。进行了VEMPs和CDP研究。我们选取了67例后半规管BPPV患者，并将他们与60名健康受试者进行比较。
BPPV组49.25%的患者出现异常颈肌VEMPs，而对照组为16.67%。61.19%的患者眼肌VEMPs发生改变，健康受试者为6.67%。复发性BPPV患者的异常眼肌VEMPs具有统计学意义。与CDP结果无显著相关性。
VEMPs证实BPPV患者的椭圆囊和球囊功能障碍高于健康个体。这一结果可能与这些患者偶尔经历的不稳定症状有关。
