William M. Feinberg Award for Excellence in Clinical Stroke: Small Vessel Disease; a Big Problem, But Fixable.
作者信息
Wardlaw Joanna M
机构信息
From the Division of Neuroimaging Science, Centre for Clinical Brain Science, Edinburgh Imaging and UK Dementia Research Institute at the University of Edinburgh.
出版信息
Stroke. 2018 Jul;49(7):1770-1775. doi: 10.1161/STROKEAHA.118.021184. Epub 2018 Jun 12.
Abstract
摘要
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Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable.腔隙周围扩大（perivascular spaces）负担，一种新兴的脑小血管疾病标志物，具有高度遗传性。
Stroke. 2018 Feb;49(2):282-287. doi: 10.1161/STROKEAHA.117.019309. Epub 2018 Jan 8.
2
MRI measurements of Blood-Brain Barrier function in dementia: A review of recent studies.MRI 测量痴呆患者血脑屏障功能：近期研究综述。
Neuropharmacology. 2018 May 15;134(Pt B):259-271. doi: 10.1016/j.neuropharm.2017.10.034. Epub 2017 Oct 28.
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Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing.脑小血管病脑血管反应性测量：MRI 采集和图像处理方案的原理和可重复性。
Int J Stroke. 2018 Feb;13(2):195-206. doi: 10.1177/1747493017730740. Epub 2017 Sep 21.
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Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination.预防脑小血管病所致认知衰退和痴呆：LACI-1 试验。一项 IIa 期剂量递增试验的方案和统计分析计划，分别和联合测试单硝酸异山梨酯和西洛他唑的耐受性、安全性和对中介终点的影响。
Int J Stroke. 2018 Jul;13(5):530-538. doi: 10.1177/1747493017731947. Epub 2017 Sep 14.
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Small Vessel Disease and Dietary Salt Intake: Cross-Sectional Study and Systematic Review.小血管疾病与膳食盐摄入量：横断面研究与系统评价
J Stroke Cerebrovasc Dis. 2017 Dec;26(12):3020-3028. doi: 10.1016/j.jstrokecerebrovasdis.2017.08.004. Epub 2017 Sep 8.
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Nonlinear temporal dynamics of cerebral small vessel disease: The RUN DMC study.脑小血管病的非线性时间动态变化：RUN DMC研究
Neurology. 2017 Oct 10;89(15):1569-1577. doi: 10.1212/WNL.0000000000004490. Epub 2017 Sep 6.
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Quantitative and qualitative MRI evaluation of cerebral small vessel disease in an elderly population: a longitudinal study.老年人群脑小血管病的定量和定性MRI评估：一项纵向研究。
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Early life risk factors for cerebrovascular disease: A systematic review and meta-analysis.脑血管疾病的早期生活危险因素：系统评价与荟萃分析
Neurology. 2017 Mar 7;88(10):976-984. doi: 10.1212/WNL.0000000000003687. Epub 2017 Feb 10.
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