Hashimoto Kazuhiko, Nishimura Shunji, Kakinoki Ryosuke, Akagi Masao
Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama, Osaka 589-8511, Japan.
Mol Clin Oncol. 2018 Jul;9(1):62-65. doi: 10.3892/mco.2018.1631. Epub 2018 May 18.
Intraosseous lipomas occurring in the bones of the upper limbs are very rare. The tumor often occurs in long bones, especially the calcaneus. Usually patients with intraosseous lipomas present with mild clinical features. Thus far, bone destruction caused by the tumor has not been reported. The present study reported a case of an aggressive intraosseous lipoma that developed in the intermediate phalanges of the thumb. This is an extremely rare case with extraosseous development, which occurred at a rare site. A 47-year old woman presented to us with right thumb pain and swelling. Computed tomography and magnetic resonance imaging revealed a mass extending to the outer edge of the phalangeal bone. The patient was treated with surgery the remove the tumor. Artificial bone was used to refill the area due to the lack of cancellous bone. During the clinical management of lipomas, it is important to consider that intraosseous lipomas may spread out of the bone; moreover, the tumor should be removed immediately to help reduce the possibility of bone destruction.
发生在上肢骨骼的骨内脂肪瘤非常罕见。该肿瘤常发生于长骨，尤其是跟骨。骨内脂肪瘤患者通常表现出轻微的临床特征。迄今为止，尚未有该肿瘤导致骨质破坏的报道。本研究报告了一例发生于拇指中节指骨的侵袭性骨内脂肪瘤病例。这是一例极其罕见的伴有骨外生长的病例，且发生在罕见部位。一名47岁女性因右拇指疼痛和肿胀前来就诊。计算机断层扫描和磁共振成像显示有一个肿块延伸至指骨外缘。患者接受了手术切除肿瘤治疗。由于松质骨缺失，使用人工骨填充该区域。在脂肪瘤的临床处理中，重要的是要考虑到骨内脂肪瘤可能扩散至骨外；此外，应立即切除肿瘤以降低骨质破坏的可能性。
