Douglass E C, Green A A, Wrenn E, Champion J, Shipp M, Pratt C B
Med Pediatr Oncol. 1985;13(4):187-90. doi: 10.1002/mpo.2950130405.
Nine of 11 patients with hepatoblastoma treated with cisplatin (DDP) based chemotherapy had a complete (CR) or partial (PR) remission. Five of these patients had measurable pulmonary disease and four achieved a CR of pulmonary lesions. The average interval of disease control following DDP was three times that of Adriamycin (ADR). DDP is an effective agent in the treatment of hepatoblastoma.
11例接受以顺铂(DDP)为基础的化疗的肝母细胞瘤患者中,有9例获得了完全缓解(CR)或部分缓解(PR)。其中5例患者有可测量的肺部疾病,4例肺部病变获得CR。顺铂治疗后疾病控制的平均间隔时间是阿霉素(ADR)的三倍。顺铂是治疗肝母细胞瘤的有效药物。