Agarwala Sandeep, Gupta Alisha, Bansal Deepak, Vora Tushar, Prasad Maya, Arora Brijesh, Kapoor Gauri, Chinnaswamy Girish, Radhakrishnan Venkatraman, Laskar Siddharth, Kaur Tanvir, Dhaliwal Rupinder Singh, Rath G K, Bakhshi Sameer
Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India.
Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Pediatr. 2017 Jun;84(6):456-464. doi: 10.1007/s12098-017-2301-9. Epub 2017 Mar 29.
Dramatic advancement has been made in the management of children with hepatoblastoma (HB) over the past 3 decades owing to the improvement in diagnostic imaging, new chemotherapeutic agents, better surgical care and availability of liver transplantation. These advances are the end results of contributions from 4 major study groups across the globe including International Society of Pediatric Oncology - Liver Tumor Strategy Group (SIOPEL), Children's Oncology Group (COG), German Pediatric Hematology Oncology Group (GPOH) and Japanese Pediatric Liver Tumor Study Group (JPLT). The current manuscript is written with the objective of developing a consensus guideline for practitioners at a National level. Based on literature and personal experience over last 3 decades, the Indian Council of Medical Research (ICMR) Expert group has made recommendations for management of children with HB in resource-challenged nations including India.
在过去30年里，由于诊断成像技术的改进、新型化疗药物的出现、更好的外科治疗以及肝移植的可及性，儿童肝母细胞瘤（HB）的管理取得了显著进展。这些进展是全球4个主要研究小组共同努力的成果，包括国际儿科肿瘤学会 - 肝脏肿瘤策略小组（SIOPEL）、儿童肿瘤学组（COG）、德国儿科血液肿瘤学组（GPOH）和日本儿科肝脏肿瘤研究组（JPLT）。本手稿旨在为国家层面的从业者制定一份共识指南。基于过去30年的文献和个人经验，印度医学研究理事会（ICMR）专家组针对包括印度在内的资源匮乏国家中儿童HB的管理提出了建议。
