Xiao Shi-ji, Liu Zhen, Zhang Mao-sheng, Chen Yong-zheng, Nie Xu-qiang, Zhang Jian-yong, He Yu-qi, Shi Jing-shan
Yao Xue Xue Bao. 2016 Jul;51(7):1117-20.
In this study, seven bibenzyl compounds were isolated from the stem of Dendrobium nobile by silica gel, MCI column chromatographic and preparative HPLC technology. By using spectroscopic techniques including NMR and MS, these compounds were identified as 4,α-dihydroxy-3,5,3’-trimethoxybibenzyl (1), 4,5-dihydroxy-3,3’,α-trimethoxybibenzyl (2), 4,4’-dihydroxy-3,5,3’-trimethoxybibenzyl (3), 4,5-dihydroxy-3,3’-dimethoxybibenzyl(4), 4,3’-dihydroxy-3,5-dimethoxybibenzyl (5), 5,4’-dihydroxy-3,3’-dimethoxybibenzyl (6) and 5,3’-dihydroxy-3-methoxybibenzyl (7). Compound 1 is a new compound and compound 4 was isolated from this plant for the first time.
在本研究中，通过硅胶、MCI柱色谱和制备型高效液相色谱技术，从金钗石斛茎中分离出7种联苄化合物。利用包括核磁共振（NMR）和质谱（MS）在内的光谱技术，将这些化合物鉴定为4,α-二羟基-3,5,3'-三甲氧基联苄（1）、4,5-二羟基-3,3',α-三甲氧基联苄（2）、4,4'-二羟基-3,5,3'-三甲氧基联苄（3）、4,5-二羟基-3,3'-二甲氧基联苄（4）、4,3'-二羟基-3,5-二甲氧基联苄（5）、5,4'-二羟基-3,3'-二甲氧基联苄（6）和5,3'-二羟基-3-甲氧基联苄（7）。化合物1是一种新化合物，化合物4首次从该植物中分离得到。
