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先天性心脏病患者的同期心律失常手术

Concomitant arrhythmia surgery in patients with congenital heart disease.

作者信息

Ramdjan Tanwier T T K, Mouws Elisabeth M J P, Kik Charles, Roos-Hesselink Jolien W, Bogers Ad J J C, de Groot Natasja M S

机构信息

Department of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands.

出版信息

Interact Cardiovasc Thorac Surg. 2018 Dec 1;27(6):902-909. doi: 10.1093/icvts/ivy181.

Abstract

OBJECTIVES

Atrial tachyarrhythmia, including atrial fibrillation (AF), atrial flutter (AFL) and intra-atrial reentrant tachycardia (IART), occur frequently in patients with congenital heart disease (CHD), who may undergo multiple surgical procedures throughout life. However, data on the effectiveness of concomitant arrhythmia surgery in CHD patients are scarce.

METHODS

Outcome of concomitant arrhythmia surgery for AF or AFL/IART was examined in 66 successive patients [31 men (47%); age at surgery: 56 ± 14 (24-78) years] with various CHD.

RESULTS

Concomitant arrhythmia surgery was performed in patients with a history of only AF (n = 46, 70%), only AFL/IART (n = 6, 9%) or a combination of AF and AFL/IART (n = 14, 21%). Median follow-up after arrhythmia surgery was 2 (1-4) years. AF reoccurred in 40 patients (67%), of whom 13 (22%) only had early recurrences; none of the patients with only AFL or IART prior to arrhythmia surgery developed AF after arrhythmia surgery. Recurrence-free survival of late AF was 4.6 years and differed according to the type of AF prior to surgery. Late recurrence-free survival at 3-year follow-up was 71% for paroxysmal AF, 45% for persistent AF and 20% for long-standing persistent AF (P = 0.047). Age at arrhythmia surgery was an independent predictor for late AF recurrence (odds ratio 1.05, P = 0.006). AFL/IART occurred in 17 patients (26%) after arrhythmia surgery, which was de novo in 11 patients (17%).

CONCLUSIONS

Arrhythmia surgery in CHD patients results in freedom from late AF recurrence for a small majority of patients after median follow-up of 2 years. (Long-standing) persistent AF and older age at arrhythmia surgery are related to higher recurrence rates.

摘要

目的

房性快速性心律失常,包括心房颤动(AF)、心房扑动(AFL)和房内折返性心动过速(IART),在先天性心脏病(CHD)患者中频繁发生,这些患者一生中可能需要接受多次外科手术。然而,关于先天性心脏病患者同期心律失常手术有效性的数据却很匮乏。

方法

对66例连续的患有各种先天性心脏病的患者[31例男性(47%);手术年龄:56±14(24 - 78)岁]进行了房颤或房扑/房内折返性心动过速同期心律失常手术的结果研究。

结果

同期心律失常手术在仅有房颤病史的患者中进行了46例(70%),仅有房扑/房内折返性心动过速的患者中进行了6例(9%),房颤与房扑/房内折返性心动过速合并存在的患者中进行了14例(21%)。心律失常手术后的中位随访时间为2(1 - 4)年。40例患者(67%)房颤复发,其中13例(22%)仅早期复发;心律失常手术前仅有房扑或房内折返性心动过速的患者在心律失常手术后均未发生房颤。晚期房颤的无复发生存期为4.6年,且根据手术前房颤类型不同而有所差异。3年随访时阵发性房颤的晚期无复发生存率为71%,持续性房颤为45%,长期持续性房颤为20%(P = 0.047)。心律失常手术时的年龄是晚期房颤复发的独立预测因素(比值比1.05,P = 0.006)。心律失常手术后17例患者(26%)发生房扑/房内折返性心动过速,其中11例(17%)为新发。

结论

先天性心脏病患者的心律失常手术在中位随访2年后,一小部分患者实现了晚期房颤无复发。(长期)持续性房颤和心律失常手术时年龄较大与较高的复发率相关。

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