Guerrier Karine, Hendrickson Benjamin, Waller B Rush, Wetzel Glenn T
Le Bonheur Children's Hospital, The Heart Institute, 49 N Dunlap, 3rd Floor, Memphis, TN, 38103, USA.
Curr Treat Options Cardiovasc Med. 2019 Jul 25;21(9):44. doi: 10.1007/s11936-019-0749-9.
Adult survivors of congenital heart disease (CHD) are at increased risk of arrhythmia. The goal of this review is to outline diagnostic and therapeutic approaches to arrhythmia in adult CHD patients.
Macro-reentrant atrial tachyarrhythmia is the most common arrhythmia encountered in adults with CHD. Approximately 25% of hospitalizations associated with arrhythmia. The risk of ventricular arrhythmia is estimated as high as 25-100 times that for the general population and increased after two decades. Routine ambulatory monitoring is important for arrhythmia risk assessment in adults with CHD. There are limitations, potential adverse effects, and risk of recurrence with antiarrhythmic drugs, catheter ablation, and surgical approaches. Adults with CHD suffer various forms of arrhythmia, are at increased risk of sudden death, and require special consideration for medical and interventional therapy.
先天性心脏病(CHD)成年幸存者发生心律失常的风险增加。本综述的目的是概述成年CHD患者心律失常的诊断和治疗方法。
大折返性房性快速心律失常是成年CHD患者中最常见的心律失常。约25%的住院与心律失常有关。室性心律失常的风险估计比一般人群高25至100倍,且在二十年后增加。常规动态监测对成年CHD患者的心律失常风险评估很重要。抗心律失常药物、导管消融和手术方法存在局限性、潜在不良反应和复发风险。成年CHD患者会发生各种形式的心律失常,猝死风险增加,在药物和介入治疗方面需要特殊考虑。