Department of Biosciences, Durham University, Stockton Road, Durham, UK.
J Exp Bot. 2018 Aug 31;69(19):4625-4632. doi: 10.1093/jxb/ery222.
In recent years, post-translational modification (PTM) of proteins has emerged as a key process that integrates plant growth and response to a changing environment. During the processes of domestication and breeding, plants were selected for various yield and adaptational characteristics. The post-translational modifier small ubiquitin-like modifier (SUMO) protein is known to have a role in the regulation of a number of these characteristics. Using bioinformatics, we mined the genomes of cereal and Brassica crops and their non-crop relatives Arabidopsis thaliana and Brachypodium distachyon for ubiquitin-like protease (ULP) SUMO protease sequences. We discovered that the SUMO system in cereal crops is disproportionately elaborate in comparison with that in B. distachyon. We use these data to propose deSUMOylation as a mechanism for specificity in the SUMO system.
近年来，蛋白质的翻译后修饰（PTM）已成为整合植物生长和对环境变化响应的关键过程。在驯化和选育过程中，植物被选择具有各种产量和适应性特征。已知翻译后修饰小分子泛素样修饰（SUMO）蛋白在调节其中许多特征中发挥作用。我们使用生物信息学方法，从谷物和芸薹属作物及其非作物近亲拟南芥和短柄草的基因组中挖掘泛素样蛋白酶（ULP）SUMO 蛋白酶序列。我们发现，与短柄草相比，谷物作物中的 SUMO 系统复杂得多。我们利用这些数据提出去 SUMO 化作为 SUMO 系统特异性的一种机制。
