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接受自体造血干细胞移植患者的心血管风险与锥度指数的应用

Cardiovascular risk and use of conicity index in patients submitted to autologous hematopoietic stem cell transplantation.

作者信息

Morais Suelyne Rodrigues de, Viana Ana Carolina Cavalcante, Daltro Ana Filomena Camacho Santos, Mendonça Priscila da Silva

机构信息

Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brazil.

出版信息

Einstein (Sao Paulo). 2018 Jun 7;16(2):eAO4253. doi: 10.1590/S1679-45082018AO4253.

DOI:10.1590/S1679-45082018AO4253
PMID:29898091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5995550/
Abstract

OBJECTIVE

To analyze the prevalence of overweight and the use of conicity index for cardiovascular risk assessment in individuals submitted to autologous hematopoietic stem cell transplantation.

METHODS

The sample comprised 91 patients of both sexes, who underwent autologous hematopoietic stem cell transplantation from September 2008 to December 2013, aged 18 years or over. To determine the nutritional profile, we collected anthropometric data on weight, height, waist circumference upon hospital admission. The body mass index and the conicity index were calculated.

RESULTS

A total of 91 patients diagnosed with multiple myeloma, Hodgkin's lymphoma, non-Hodgkin's lymphoma and other conditions were evaluated. The mean age was 43.5 (14.2) years, 63.7% were male. We verified that according to the body mass index, 63.7% were overweight and, according to waist circumference, 74.7% had a higher risk for cardiovascular diseases. According to the calculation of the conicity index, 92.3% of patients presented increased cardiovascular risk. Patients with multiple myeloma had a higher conicity index when compared to other patients (p<0.01).

CONCLUSION

This study revealed a high prevalence of overweight and cardiovascular risk. It should be noted that the conicity index was a good method to evaluate cardiovascular risk and that new studies using this index should be performed.

摘要

目的

分析接受自体造血干细胞移植的个体中超重的患病率以及使用锥度指数进行心血管风险评估的情况。

方法

样本包括91名年龄在18岁及以上的男女患者,他们于2008年9月至2013年12月接受了自体造血干细胞移植。为确定营养状况,我们收集了入院时的体重、身高、腰围等人体测量数据。计算了体重指数和锥度指数。

结果

共评估了91名被诊断为多发性骨髓瘤、霍奇金淋巴瘤、非霍奇金淋巴瘤和其他疾病的患者。平均年龄为43.5(14.2)岁,63.7%为男性。我们发现,根据体重指数,63.7%的患者超重,根据腰围,74.7%的患者有较高的心血管疾病风险。根据锥度指数计算,92.3%的患者心血管风险增加。与其他患者相比,多发性骨髓瘤患者的锥度指数更高(p<0.01)。

结论

本研究揭示了超重和心血管风险的高患病率。应注意的是,锥度指数是评估心血管风险的一种好方法,应开展使用该指数的新研究。

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Methods for classifying obesity in spinal cord injury: a review.脊髓损伤中肥胖的分类方法:综述
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Comprehensive evaluation of nutritional status before and after hematopoietic stem cell transplantation in 170 patients with hematological diseases.170例血液病患者造血干细胞移植前后营养状况的综合评估
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Association of the conicity index with diabetes and hypertension in Brazilian women.巴西女性中圆锥度指数与糖尿病和高血压的关联。
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Serum Fetuin A Levels: Are They a Reliable Marker for Hepatic Steatosis and Regional Adiposity in Renal Transplant Recipients?血清胎球蛋白A水平:它们是肾移植受者肝脂肪变性和局部脂肪堆积的可靠标志物吗?
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