Nagesh S V Setlur, Shankar A, Krebs J, Hinaman J, Bednarek D R, Rudin S
Toshiba Stroke and Vascular Research Center, University at Buffalo, SUNY.
Proc SPIE Int Soc Opt Eng. 2018 Feb;10573. doi: 10.1117/12.2294535. Epub 2018 Mar 9.
Real-time visualization of fine details ranging to 100 um or less in neuro-vascular imaging guided interventions is important. A separate high-resolution detector mounted on a standard flat panel detector (FPD) was previously reported. This device had to be rotated mechanically into position over the FPD for high resolution imaging. Now, the new detector reported here has a high definition (Hi-Def) zoom capability along with the FPD built into one unified housing. The new detector enables rapid switching, by the operator between Hi-Def and FPD modes. Standard physical metrics comparing the new Hi-Def modes with those of the FPD are reported, demonstrating improved imaging resolution and noise capability at patient doses similar to those used for the FPD. Semi-quantitative subjective studies involving qualitative clinician feedback on images of interventional devices such as a Pipeline Embolization Device (PED) acquired in both Hi-Def and FPD modes are presented. The PED is deployed in a patient specific 3D printed neuro-vascular phantom embedded inside realistic bone and with tissue attenuating material. Field-of-view (FOV), exposure and magnification were kept constant for FPD and Hi-Def modes. Static image comparisons of the same view of the PED within the phantom were rated by expert interventionalists who chose from the following ratings: Similar, Better, or Superior. Generally, the Hi-Def zoomed images were much preferred over the FPD, indicating the potential to improve endovascular procedures and hence outcomes using such a Hi-Def feature.
在神经血管成像引导介入中实时可视化100微米及以下的精细细节非常重要。此前有报道称,在标准平板探测器(FPD)上安装了一个单独的高分辨率探测器。该设备必须通过机械旋转到FPD上方的位置才能进行高分辨率成像。现在,这里报道的新型探测器具有高清晰度(Hi-Def)变焦功能,并且FPD内置在一个统一的外壳中。新型探测器使操作员能够在Hi-Def模式和FPD模式之间快速切换。报告了将新型Hi-Def模式与FPD模式进行比较的标准物理指标,表明在与FPD使用的剂量相似的患者剂量下,成像分辨率和噪声能力得到了改善。本文还介绍了半定量主观研究,其中包括临床医生对在Hi-Def和FPD模式下获取的介入设备(如Pipeline栓塞装置(PED))图像的定性反馈。PED部署在一个患者特异性的3D打印神经血管模型中,该模型嵌入逼真的骨骼中,并带有组织衰减材料。FPD和Hi-Def模式下的视野(FOV)、曝光和放大倍数保持恒定。由专家介入医生对模型中PED同一视图的静态图像进行比较评分,他们从以下评分中选择:相似、更好或更优。一般来说,Hi-Def变焦图像比FPD图像更受青睐,这表明使用这种Hi-Def功能有潜力改善血管内手术并因此改善治疗结果。