Akhvlediani N D, Matyukhov I P
I.M. Sechenov First MSMU of Minzdrav of Russia, Moscow, Russia.
Urologiia. 2018 May(2):142-146.
Sildenafil is the first phosphodiesterase type 5 inhibitor (PDE-5), used in the management of erectile dysfunction (ED). The effectiveness and safety of the original drug have been studied most extensively among ED medications. Sildenafil has been successfully used for ED of different etiology and severity. To date, this PDE-5 remains the drug of choice for many patients with erectile dysfunction.
西地那非是首个5型磷酸二酯酶抑制剂(PDE - 5),用于治疗勃起功能障碍(ED)。在治疗ED的药物中,原研药的有效性和安全性得到了最广泛的研究。西地那非已成功用于治疗不同病因和严重程度的ED。迄今为止,这种PDE - 5仍然是许多勃起功能障碍患者的首选药物。