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肌间沟阻滞对肺叶切除术患者同侧肩部疼痛及肺功能的影响:一项随机对照试验。

The effect of interscalene block on ipsilateral shoulder pain and pulmonary function in patients undergoing lung lobectomy: A randomized controlled trial.

作者信息

Woo Jae Hee, Kim Youn Jin, Kim Kwan Chang, Kim Chi Hyo, Jun Jeeyoung

机构信息

Department of Anesthesiology and Pain Medicine Department of Thoracic and Cardiovascular Surgery, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.

出版信息

Medicine (Baltimore). 2018 Jun;97(24):e11034. doi: 10.1097/MD.0000000000011034.

DOI:10.1097/MD.0000000000011034
PMID:29901598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6023789/
Abstract

BACKGROUND

Postoperative ipsilateral shoulder pain occurs in 37% to 68% of patients undergoing a thoracotomy. We examined whether interscalene brachial plexus block using a lower concentration of local anesthetic would reduce the incidence of post-thoracotomy ipsilateral shoulder pain with assessment of pulmonary function in patients who underwent a lung lobectomy.

METHODS

Forty-four patients who underwent a lung lobectomy were randomly assigned to either the control or the interscalene block group. Single-shot interscalene block on the surgical site side was performed using ropivacaine 0.25% 10 mL including dexamethasone 5 mg under ultrasound guidance in the interscalene block group. Lobectomy and continuous paravertebral block were performed under general anesthesia. The presence of ipsilateral shoulder pain and postoperative adverse events were assessed. Pulmonary function tests were performed preoperatively, the day after surgery, and the day after removing the chest tube.

RESULTS

The incidence of ipsilateral shoulder pain was significantly lower in the interscalene block group than in the control group (54.5% vs 14.3%, P = .006) with an overall incidence of 34.9%. Postoperative adverse events were similar between the groups, with no patients presenting symptoms of respiratory difficulty. Significant reductions in pulmonary function were observed in all patients after lobectomy; however, no significant difference in any of the pulmonary function test variables was observed postoperatively between the groups.

CONCLUSIONS

Interscalene block using 10 mL of 0.25% ropivacaine including dexamethasone 5 mg reduced the incidence of post-thoracotomy ipsilateral shoulder pain and did not result in additional impairment of pulmonary function.

摘要

背景

开胸手术患者中,术后同侧肩部疼痛的发生率为37%至68%。我们研究了使用较低浓度局部麻醉剂的肌间沟臂丛神经阻滞是否会降低肺叶切除术后患者的开胸术后同侧肩部疼痛发生率,并评估其肺功能。

方法

44例行肺叶切除术的患者被随机分为对照组或肌间沟阻滞组。肌间沟阻滞组在超声引导下,使用含5 mg地塞米松的0.25% 10 ml罗哌卡因对手术部位侧进行单次肌间沟阻滞。在全身麻醉下进行肺叶切除术和连续椎旁阻滞。评估同侧肩部疼痛的存在情况和术后不良事件。在术前、术后第1天和拔除胸管后第1天进行肺功能测试。

结果

肌间沟阻滞组同侧肩部疼痛的发生率显著低于对照组(54.5%对14.3%,P = 0.006),总体发生率为34.9%。两组术后不良事件相似,无患者出现呼吸困难症状。所有患者在肺叶切除术后肺功能均显著下降;然而,术后两组间任何肺功能测试变量均无显著差异。

结论

使用含5 mg地塞米松的10 ml 0.25%罗哌卡因进行肌间沟阻滞可降低开胸术后同侧肩部疼痛的发生率,且不会导致肺功能的额外损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/7e430f36adc5/medi-97-e11034-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/59692e80e2bc/medi-97-e11034-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/9700c4afef49/medi-97-e11034-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/7e430f36adc5/medi-97-e11034-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/59692e80e2bc/medi-97-e11034-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/9700c4afef49/medi-97-e11034-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6023789/7e430f36adc5/medi-97-e11034-g005.jpg

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