Gramática Luis, Cecenarro Rodolfo Raúl, Antueno Facundo Jorge, Villablanca Noelia Susana
Hospital Nacional de Clínicas - FCM - UNC.
Rev Fac Cien Med Univ Nac Cordoba. 2017 Dec 14;74(4):361-364. doi: 10.31053/1853.0605.v74.n4.15594.
Show our experience performing the minimally invasive video-assisted parathyroidectomy with central approach for the treatment of patients with primary hyperparathyroidism without using intraoperative parathyroid hormone monitoring (IPTHM) based solely on the concordance of two preoperative localization studies.
An informed consent for the accomplishment of a minimally invasive approach was performed on 27 selected patients diagnosed with primary hyperparathyroidism who underwent pre-operative cervical ultrasound and sesta-MIBI scintigraphy studies, which were consistent across them. None had a family history that might indicate a multiple endocrine neoplasia (MEN), known thyroid disease, previous neck incision, or suspicion of carcinoma. Surgery was performed through a 1.5 cm central cervical incision and the use of harmonic scalpel. IPTHM was not performed in either case.
In all cases the topographic location of the adenoma was confirmed. No signs of hyperparathyroidism persistence or recurrence were registered after a follow-up period of 42 months. There were no recurrent nerve lesions. The average operative time was 24.5 minutes and all patients were discharged within 24 hours. The analgesic requirement was minimal and the cosmetic result satisfactory.
The minimally invasive unilateral exploration of the parathyroids with video-assisted magnification without IPTHM, under the guidance of two concordant localization studies is safe and feasible, with comparable results to those of standard technique as well as aesthetic advantages, less postoperative pain and reduced hospitalization.
展示我们仅基于两项术前定位研究结果的一致性,采用中央入路的微创视频辅助甲状旁腺切除术治疗原发性甲状旁腺功能亢进患者的经验,且术中不使用甲状旁腺激素监测(IPTHM)。
对27例经选择诊断为原发性甲状旁腺功能亢进的患者进行了微创入路手术知情同意,这些患者均接受了术前颈部超声和99m锝-甲氧基异丁基异腈(99mTc-MIBI)闪烁扫描检查,两项检查结果一致。所有患者均无可能提示多发性内分泌腺瘤病(MEN)的家族史、已知的甲状腺疾病、既往颈部手术史或怀疑有癌症。手术通过1.5 cm的颈部中央切口进行,并使用超声刀。两例均未进行IPTHM。
所有病例均证实了腺瘤的位置。随访42个月后,未发现甲状旁腺功能亢进持续或复发的迹象。无喉返神经损伤。平均手术时间为24.5分钟,所有患者均在24小时内出院。镇痛需求极小,美容效果满意。
在两项一致的定位研究指导下,不使用IPTHM,通过视频辅助放大进行微创单侧甲状旁腺探查是安全可行的,与标准技术相比结果相当,且具有美容优势、术后疼痛减轻和住院时间缩短的优点。