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溴甲烷性视神经萎缩

Methyl bromide optic atrophy.

作者信息

Chavez C T, Hepler R S, Straatsma B R

出版信息

Am J Ophthalmol. 1985 Jun 15;99(6):715-9. doi: 10.1016/s0002-9394(14)76043-x.

Abstract

A 32-year-old fumigation assistant developed systemic and neuro-ophthalmic manifestations of methyl bromide poisoning, including increased serum bromide level (6.6 mg/100 ml), paresthesias and burning dysesthesia on his hands and feet, and visual impairment. Ocular examination showed mild bilateral decrease in vision, temporal optic nerve head pallor, severely attenuated visual-evoked response amplitudes and normal latencies, a normal electroretinogram, an abnormal electrooculogram, and a severe deuteranomalous (green) defect on Farnsworth-Munsell 100-hue testing. His vision had not improved 12 months after the initial exposure.

摘要

一名32岁的熏蒸助手出现了甲基溴中毒的全身和神经眼科表现,包括血清溴化物水平升高(6.6毫克/100毫升)、手脚感觉异常和烧灼样感觉障碍,以及视力损害。眼部检查显示双眼视力轻度下降、颞侧视神经乳头苍白、视觉诱发电位振幅严重衰减但潜伏期正常、视网膜电图正常、眼电图异常,以及在Farnsworth-Munsell 100色调测试中存在严重的绿色色觉异常缺陷。初次接触后12个月,他的视力仍未改善。

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