Guo Xiangyu, Ma Qiang, Meng Xianshuang, Lü Yueguang, Wang Chuanxian, Bai Hua
Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
Wei Sheng Yan Jiu. 2017 May;46(3):467-471.
A rapid analytical method had been developed for the screening of three halogenated salicylanilines in cosmetics using ambition ionization coupled with ion mobility spectrometry.
Without time-consuming pretreatment, cosmetic samples of lotion, lipstick and powder were added or smudged onto a Grade 3MM chromatography paper for paper spray ionization, cosmetic samples of cream and shampoo were simply loaded with a metal wire probe for extraction nano-electrospray.
The limits of detection( LODs) for the three halogenated salicylanilides were 50 μg/kg. The instrumental analysis time for a single ion mobility spectrometry run was less than 15 ms. The suspected positive samples were subjected to further verification by high-performance liquid chromatography coupled with tandem mass spectrometry.
The method is simple, rapid, and with low cost and is suitable for rapid, on-site screening of cosmetics.
建立了一种快速分析方法，用于采用大气压电离结合离子淌度质谱法筛查化妆品中的三种卤代水杨酰苯胺。
无需耗时的预处理，将乳液、口红和散粉等化妆品样品添加或涂抹到3MM层析纸上进行纸喷雾电离，将面霜和洗发水等化妆品样品用金属丝探针简单加载进行萃取纳喷电喷雾。
三种卤代水杨酰苯胺的检测限（LOD）为50μg/kg。单次离子淌度质谱运行的仪器分析时间小于15毫秒。疑似阳性样品通过高效液相色谱-串联质谱法进行进一步验证。
该方法简单、快速、成本低，适用于化妆品的快速现场筛查。
