Su Meifang, Chen Xiaoying, Xiao Tian, Li Songtao, Ying Xuhua, Jiang Qingwu, Fu Chaowei
Yuhuan County Center of Disease Control and Prevention, Taizhou 317600, China.
Wei Sheng Yan Jiu. 2017 Sep;46(5):749-754.
To explore related factors for early-onset type 2 diabetes mellitus( EOD) in rural Chinese adults.
Totally, 1695 newly diagnosed cases of type 2 diabetes mellitus( T2DM) were recruited from baseline survey of Yuhuan Rural Adults Cohort for Diabetes during June to December 2012 in Yuhuan County, Zhejiang Province, China, and divided into EOD or late-onset type 2 diabetes mellitus( LOD) with their diagnosis age at ≤ 40 or > 40 years, respectively. Diagnosis age was compared among different characteristics. Logistic regression was used to analyze related factors in EOD.
Among 1695 new T2 DM cases, near half( 47. 3%) were men and 85( 5. 0%) were grouped into EOD. Their mean age at diagnosis of T2 DM was( 60. 39 ±12. 49) years overall. Men or those with more than 9 education years, family average personal income ≥2000 Yuan per month, less occupational physical activities, smoking, drinking, overweight and family history of T2 DM had lower average age at diagnosis than women or those without them, while those with regular physical exercise had higher that than those without that. After the adjustment for other covariates, multiple logistic regression showed that more than 9 education years( OR = 6. 62, 95% CI 3. 87-11. 32), family average personal income ≥2000 Yuan per month( OR = 6. 60, 95% CI 3. 32-13. 12), and regular physical exercise( OR = 0. 37, 95% CI 0. 17-0. 80) were independently correlated to EOD.
Education level, income, and regular exercise are significantly correlated to EOD in rural Chinese adults.
探讨中国农村成年人早发型2型糖尿病（EOD）的相关因素。
2012年6月至12月，在中国浙江省玉环县进行的玉环农村成年人糖尿病队列基线调查中，共招募了1695例新诊断的2型糖尿病（T2DM）患者，并根据诊断年龄≤40岁或>40岁分别分为EOD组或晚发型2型糖尿病（LOD）组。比较不同特征人群的诊断年龄。采用逻辑回归分析EOD的相关因素。
在1695例新诊断的T2DM患者中，近一半（47.3%）为男性，85例（5.0%）被归入EOD组。总体上，他们T2DM的平均诊断年龄为（60.39±12.49）岁。男性或受教育年限超过9年、家庭人均月收入≥2000元、职业体力活动较少、吸烟、饮酒、超重以及有T2DM家族史的患者，其诊断时的平均年龄低于女性或无上述情况者，而经常进行体育锻炼的患者诊断时的平均年龄高于未锻炼者。在对其他协变量进行调整后，多因素逻辑回归显示，受教育年限超过9年（OR=6.62，95%CI 3.87-11.32）、家庭人均月收入≥2000元（OR=6.60，95%CI 3.32-13.12）以及经常进行体育锻炼（OR=0.37，95%CI 0.17-0.80）与EOD独立相关。
教育水平、收入和规律锻炼与中国农村成年人的EOD显著相关。
