Zhu Bingbing, Dong Xiaolian, Zhu Jianfu, Wang Na, Chen Yue, Jiang Qingwu, Fu Chaowei
School of Public Health, MOE Key Laboratory of Public Health Safety, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, China.
Deqing County Center for Disease Prevention and Control, Huzhou 313200, China.
Wei Sheng Yan Jiu. 2022 Jan;51(1):12-17. doi: 10.19813/j.cnki.weishengyanjiu.2022.01.003.
To explore the associations between tea drinking and the incident risk of type 2 diabetes mellitus(T2 DM).
A dynamic prospective cohort study among a total of 27 841 diabetes-free permanent adult residents randomly selected from 2, 6 and 7 rural communities between 2006-2008, 2011-2012 and 2013-2014, respectively. Questionnaire survey, physical examination, and laboratory test were carried out among the participants. In 2018, we conducted a follow-up through the electronic health records of residents. Cox regression model were applied to explore the association between tea drinking and the incident risk of T2 DM and estimate the hazard ratio(HR), and its 95%CI.
Among the 27 841 rural community residents in Deqing County, there were 10 726(38.53%) were tea drinkers, 8215 of which were green tea drinkers, accounting for 76.59%. Totally 883 new T2 DM incidents were identified until December 31, 2018, and the incidence density was 4.43 per 1000 person years(PYs). The incidence density was 4.07/1000 PYs in those with tea drinking habits and 4.71/1000 PYs in those without tea drinking habits, among which the incidence density was 3.79/1000 PYs in those with green tea drinking habits. After controlling for sex, age, education, farming, smoking, alcohol consumption, dietary preference, body mass index, hypertension, impaired fasting glucose, family history of diabetes, the risk of T2 DM among rural residents with tea drinking habits in Deqing County was 0.79 times higher than that among residents without tea drinking habits(HR=0.79, 95%CI 0.65-0.96), and the risk of T2 DM among residents with green tea drinking habits was 0.72 times higher than that among residents without tea drinking habits(HR=0.72, 95%CI 0.58-0.89). However, no significant associations were found between other kinds of tea and the risk of T2 DM, nor the amount of green tea to drink.
Drinking green tea may reduce the risk of T2 DM among adult population in rural China.
探讨饮茶与2型糖尿病（T2 DM）发病风险之间的关联。
对2006 - 2008年、2011 - 2012年和2013 - 2014年分别从2个、6个和7个农村社区随机选取的27841名无糖尿病的成年常住居民进行动态前瞻性队列研究。对参与者进行问卷调查、体格检查和实验室检测。2018年，通过居民电子健康记录进行随访。应用Cox回归模型探讨饮茶与T2 DM发病风险之间的关联，并估计风险比（HR）及其95%置信区间。
在德清县的27841名农村社区居民中，有10726人（38.53%）饮茶，其中8215人饮用绿茶，占76.59%。截至2018年12月31日，共发现883例新的T2 DM病例，发病密度为每1000人年4.43例。有饮茶习惯者的发病密度为4.07/1000人年，无饮茶习惯者为4.71/1000人年，其中饮用绿茶者的发病密度为3.79/1000人年。在控制了性别、年龄、教育程度、务农情况、吸烟、饮酒、饮食偏好、体重指数、高血压、空腹血糖受损、糖尿病家族史后，德清县有饮茶习惯的农村居民患T2 DM的风险比无饮茶习惯的居民高0.79倍（HR = 0.79，95%CI 0.65 - 0.96），饮用绿茶的居民患T2 DM的风险比无饮茶习惯的居民高0.72倍（HR = 0.72，95%CI 0.58 - 0.89）。然而，未发现其他种类的茶与T2 DM风险之间存在显著关联，也未发现绿茶饮用量与T2 DM风险之间存在显著关联。
饮用绿茶可能降低中国农村成年人群患T2 DM的风险。
