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使用基于网络的应用程序改善妇科肿瘤患者术后结局:一项随机对照可行性试验。

Use of a web-based app to improve postoperative outcomes for patients receiving gynecological oncology care: A randomized controlled feasibility trial.

机构信息

College of Medicine, University of Tennessee Health Science Center, 66 N. Pauline St., Ste. 633, Memphis, TN 38163, United States.

College of Medicine, University of Tennessee Health Science Center, 66 N. Pauline St., Ste. 633, Memphis, TN 38163, United States.

出版信息

Gynecol Oncol. 2018 Aug;150(2):311-317. doi: 10.1016/j.ygyno.2018.06.007. Epub 2018 Jun 11.

Abstract

OBJECTIVE

Nearly 1 in 5 patients hospitalized for ovarian cancer surgery are readmitted for complications that may have been prevented with monitoring. We conducted a randomized controlled feasibility trial to evaluate a postoperative web-based app intervention to provide real-time symptom monitoring among patients diagnosed or with suspected gynecological cancer who had open bilateral salpingo-oophorectomy surgery.

METHODS

Participants were randomized into two groups: (1) App + Reminder: had access to the app, and use was encouraged with daily and/or weekly reminders; (2) app: had access to the app but received no reminders. The app displayed discharge instructions and queried symptoms. Patients' self-reported health information was integrated into their electronic health records. Outcomes above a predetermined threshold triggered alerts that indicated a patient may need medical intervention. Participants completed a questionnaire at baseline and 30-day follow-up. They were also invited to provide qualitative, post-intervention feedback.

RESULTS

We screened 35 patients, with high rates of recruitment (74%, N = 26) and completion (93%, N = 24). Participants in the App + Reminder group had more frequent app use relative to the app group (p = 0.05). Using differences-in-differences (DID) analysis for quality of life, the App + Reminder group had relative increase in the mental health score (DID = 7.51, p = 0.15) but decrease in the physical health score (DID = -7.49, p = 0.13). Participant feedback suggested the relative decrease in physical quality of life was attributable to the app activating patients' focus on physical symptoms, not the intervention.

CONCLUSION

The pilot established feasibility, acceptability, and some potential benefits of a new web-based app intervention for gynecological oncology postoperative care.

摘要

目的

近五分之一因并发症而住院的卵巢癌手术患者可能因监测而避免再次入院。我们进行了一项随机对照可行性试验,以评估一种术后基于网络的应用程序干预措施,该措施旨在为接受开腹双侧输卵管卵巢切除术的妇科癌症患者或疑似妇科癌症患者提供实时症状监测。

方法

参与者被随机分为两组:(1)应用程序+提醒:可以访问应用程序,并且可以通过每日和/或每周提醒来鼓励使用;(2)应用程序:可以访问应用程序,但不接受提醒。该应用程序显示出院医嘱并查询症状。患者的自我报告健康信息被整合到他们的电子健康记录中。超过预定阈值的结果会触发警报,表明患者可能需要医疗干预。参与者在基线和 30 天随访时完成了一份问卷。他们还被邀请提供干预后的定性反馈。

结果

我们筛选了 35 名患者,招募率高(74%,N=26),完成率高(93%,N=24)。与应用程序组相比,应用程序+提醒组的应用程序使用更频繁(p=0.05)。使用差异中的差异(DID)分析方法进行生活质量评估,应用程序+提醒组的心理健康评分相对增加(DID=7.51,p=0.15),而身体健康评分相对降低(DID=-7.49,p=0.13)。参与者的反馈表明,身体质量相对下降的原因是应用程序使患者更加关注身体症状,而不是干预本身。

结论

该试验确定了一种新的基于网络的妇科肿瘤术后护理应用程序干预措施的可行性、可接受性和一些潜在益处。

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