Aarnes Turi K, Lerche Phillip, Bednarski Richard M, Hubbell John A E
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio 43210, USA.
Can Vet J. 2018 May;59(5):500-504.
This study evaluated use of midazolam, ketamine, and xylazine (MKX) for total intravenous (IV) anesthesia (TIVA) in horses. Medical records of 46 horses undergoing a clinical procedure using MKX for TIVA were reviewed. Age, breed, procedure, heart rate (HR), respiratory rate (RR), pre-anesthetic drugs, induction drugs, and total volume of MKX were recorded. Duration of anesthesia, time to standing, number of attempts to stand, and recovery score were also recorded. All horses were premedicated with an alpha-2 adrenoceptor agonist and anesthesia was induced with ketamine and midazolam. Duration of MKX infusion was 33 ± 14 min. Heart rate and RR decreased during the infusion of MKX. Time to endotracheal extubation was 19 ± 12 min. Horses stood at 33 ± 13 min. Median number of attempts to stand was 1. Maintenance of anesthesia of horses with MKX was useful for a variety of procedures and recovery from anesthesia was good.
本研究评估了咪达唑仑、氯胺酮和赛拉嗪（MKX）用于马匹全静脉麻醉（TIVA）的情况。回顾了46匹使用MKX进行TIVA临床手术的马匹的病历。记录了年龄、品种、手术、心率（HR）、呼吸频率（RR）、麻醉前用药、诱导药物以及MKX的总量。还记录了麻醉持续时间、站立时间、站立尝试次数和恢复评分。所有马匹均预先使用α-2肾上腺素能受体激动剂进行预处理，并用氯胺酮和咪达唑仑诱导麻醉。MKX输注持续时间为33±14分钟。输注MKX期间心率和RR下降。气管插管拔除时间为19±12分钟。马匹在33±13分钟时站立。站立尝试的中位数为1次。MKX用于马匹麻醉维持对各种手术有用，且麻醉恢复良好。
