Jafari Behnam, Sabz Gholamabas, Masnavi Elahe, Panahi Roghaye, Jokar Saeid, Roozbehi Amrollah, Hasanzadeh Sajad
Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran.
Department of Obstetrics and Gynecology, Yasuj University of Medical Sciences, Yasuj, Iran.
F1000Res. 2018 Mar 7;7:288. doi: 10.12688/f1000research.13787.2. eCollection 2018.
: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. : A 39-year-old man, with known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment. The patient smoked for 10 years (3 pack/year). No other findings were found in clinical examinations except for wheezing in the right lung. The patient's chest radiography was shown a mass. For further investigation, spiral CT scan was performed. Large lymph nodes on the right side of the trachea, measuring about 23 mm and a mass of 70 × 77 mm in the vicinity of the right lung hilum and a hypodense nodule in the posterior part of the liver with malignancy suspicious were reported. After several biopsy results was shown chronic granulomatous inflammation, the most important differential diagnosis is tuberculosis (TB) and sarcoidosis. Sputum smear, culture, and PCR were performed for tuberculosis. Also, the level of angiotensin-converting enzyme (ACE) was measured for sarcoidosis. the results ruled out TB and shown a higher level of ACE (ACE = 88 IU/L).After diagnosis treatment started with prednisolone. Now, the patient is in the follow- up. : In hilar lymphadenopathy of lung sarcoidosis is the importance differential diagnosis that should be considered.
结节病是一种病因不明的肉芽肿性疾病,症状表现多样,从无症状到有症状不等。几乎一半的结节病患者没有症状。在本文中,我们描述了一名肺部和肝脏受累的结节病患者;该病可能会与转移瘤相混淆。一名39岁男性,已知患有甲状腺功能减退症,在封闭环境中接触洗涤剂后因呼吸困难和咳嗽前来急诊病房就诊。该患者有10年吸烟史(每年3包)。除右肺有哮鸣音外,临床检查未发现其他异常。患者胸部X线片显示有一个肿块。为进一步检查,进行了螺旋CT扫描。报告显示气管右侧有肿大淋巴结,大小约23毫米,右肺门附近有一个70×77毫米的肿块,肝脏后部有一个低密度结节,怀疑为恶性。在多次活检结果显示为慢性肉芽肿性炎症后,最重要的鉴别诊断是结核病(TB)和结节病。对结核病进行了痰涂片、培养和PCR检测。同时,检测了血管紧张素转换酶(ACE)水平以诊断结节病。结果排除了结核病,且ACE水平较高(ACE = 88 IU/L)。确诊后开始用泼尼松龙进行治疗。现在,该患者正在接受随访。在肺结节病的肺门淋巴结肿大中,这是应考虑的重要鉴别诊断。