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低致病性禽流感(LPAI)感染的绿头鸭中免疫基因的表达:一个数据集。

Expression of immune genes and in mallard ducks infected with low pathogenic avian influenza (LPAI): A dataset.

作者信息

Helin Anu S, Wille Michelle, Atterby Clara, Järhult Josef, Waldenström Jonas, Chapman Joanne R

机构信息

Centre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, Kalmar, Sweden.

Zoonosis Science Centre, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.

出版信息

Data Brief. 2018 Apr 23;18:1562-1566. doi: 10.1016/j.dib.2018.04.061. eCollection 2018 Jun.

DOI:10.1016/j.dib.2018.04.061
PMID:29904657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5998173/
Abstract

This article provides data on primer sequences used to amplify the innate immune genes and and a set of normalizing reference genes in mallards (), and shows which reference genes are stable, per tissue, for our experimental settings. Data on the expressional changes of these two genes over a time-course of infection with low pathogenic avian influenza virus (LPAI) are provided. Individual-level data are also presented, including LPAI infection load, and per tissue gene expression of and . Gene expression in two outlier individuals is explored in more depth.

摘要

本文提供了用于扩增野鸭()先天免疫基因以及一组标准化参考基因的引物序列数据,并展示了在我们的实验设置中,每个组织中哪些参考基因是稳定的。还提供了这两个基因在低致病性禽流感病毒(LPAI)感染时间进程中的表达变化数据。同时也呈现了个体水平的数据,包括LPAI感染负荷以及每个组织中 和 的基因表达。对两个异常个体的基因表达进行了更深入的探究。

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本文引用的文献

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Mol Immunol. 2018 Mar;95:64-72. doi: 10.1016/j.molimm.2018.01.012. Epub 2018 Feb 3.
2
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PLoS One. 2016 Feb 17;11(2):e0149454. doi: 10.1371/journal.pone.0149454. eCollection 2016.
3
With Reference to Reference Genes: A Systematic Review of Endogenous Controls in Gene Expression Studies.关于参考基因:基因表达研究中内参的系统综述
PLoS One. 2015 Nov 10;10(11):e0141853. doi: 10.1371/journal.pone.0141853. eCollection 2015.
4
Sampling strategies and biodiversity of influenza A subtypes in wild birds.野生鸟类甲型流感亚型的采样策略与生物多样性
PLoS One. 2014 Mar 5;9(3):e90826. doi: 10.1371/journal.pone.0090826. eCollection 2014.
5
Long-term variation in influenza A virus prevalence and subtype diversity in migratory mallards in northern Europe.在北欧迁徙的绿头鸭中,甲型流感病毒流行率和亚型多样性的长期变化。
Proc Biol Sci. 2014 Feb 26;281(1781):20140098. doi: 10.1098/rspb.2014.0098. Print 2014 Apr 22.
6
Differential immune response of mallard duck peripheral blood mononuclear cells to two highly pathogenic avian influenza H5N1 viruses with distinct pathogenicity in mallard ducks.两种高致病性鸭源 H5N1 流感病毒对鸭外周血单核细胞免疫反应的差异及其致病性研究。
Arch Virol. 2014 Feb;159(2):339-43. doi: 10.1007/s00705-013-1820-6. Epub 2013 Aug 21.
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