Del Torso S, Kelly M J, Kalff V, Stellin G, Mee R B, Venables A W
Br Heart J. 1985 Aug;54(2):209-14. doi: 10.1136/hrt.54.2.209.
Radionuclide studies were performed to determine pulmonary blood flow in six children who had undergone surgery for pulmonary atresia, ventricular septal defect, and hypoplastic pulmonary arteries with or without major aortopulmonary collateral arteries. Lung blood flow was assessed from both particle perfusion lung scans and the pulmonary and systemic phase of a radionuclide dynamic flow study. Five patients had perfusion defects identified on the particle perfusion lung scan. In three of these, abnormal areas were perfused only during the systemic phase of the flow study, a combination of findings that indicate the presence of perfusion by collateral arteries. In one patient no systemic perfusion was noted and in one an initial particle perfusion study indicated the presence of a lung segment perfused by a collateral artery. In this last patient the particle perfusion scan after total correction showed a reduction in the size of the lung perfusion defect and no evidence of lung perfusion during the systemic phase of the flow study. The particle perfusion lung scan in the sixth patient showed pronounced asymmetry in blood flow to the lungs with no segmental perfusion defect on the particle perfusion scan and no abnormalities on the systemic flow study. It is concluded that radionuclide lung perfusion and flow studies provide useful information on lung perfusion and merit further evaluation to define their role in the management of these patients.
对6名接受过肺动脉闭锁、室间隔缺损以及发育不全的肺动脉（伴或不伴主要主肺动脉侧支动脉）手术的儿童进行了放射性核素研究，以确定肺血流量。通过颗粒灌注肺扫描以及放射性核素动态血流研究的肺和体循环期来评估肺血流量。5名患者在颗粒灌注肺扫描中发现有灌注缺损。其中3名患者，异常区域仅在血流研究的体循环期有灌注，这些综合表现表明存在侧支动脉灌注。1名患者未观察到体循环灌注，另1名患者最初的颗粒灌注研究表明存在由侧支动脉灌注的肺段。在最后这名患者中，完全矫正后的颗粒灌注扫描显示肺灌注缺损面积减小，且在血流研究的体循环期未发现肺灌注迹象。第6名患者的颗粒灌注肺扫描显示肺血流明显不对称，颗粒灌注扫描未发现节段性灌注缺损，体循环血流研究也未发现异常。结论是，放射性核素肺灌注和血流研究为肺灌注提供了有用信息，值得进一步评估以明确其在这些患者管理中的作用。
