University of Michigan Medical School, Ann Arbor, Michigan.
Department of Pathology, University of Michigan, Ann Arbor, Michigan.
Oper Neurosurg (Hagerstown). 2019 May 1;16(5):E154-E158. doi: 10.1093/ons/opy158.
Neurocysticercosis (NCC) is an infectious helminthic disease often presenting in patients who have immigration or travel history from areas where NCC is endemic. Fourth ventricle cysts from NCC pose a unique treatment challenge, as there is little consensus on the best treatment. This case study describes the treatment of a patient with fourth ventricle neurocysticercosis (FVNCC), examines the therapeutic decision-making, and provides a video of a posterior fossa craniotomy (PFC) resection of a degenerative cyst.
The patient presented with headache, dizziness, nausea, and memory difficulties. A fourth ventricle cyst consistent with NCC was found on magnetic resonance imaging, and serum enzyme-linked immunosorbent assay (ELISA) confirmed the diagnosis. The cyst was removed utilizing an open PFC followed by antihelminthic therapy and corticosteroids. There was resolution of symptoms at 9 mo postoperatively.
Several treatment modalities have been proposed for isolated cysts in the fourth ventricle, including medication, ventriculoperitoneal shunt, endoscopic removal, and PFC. The treatment decision is complex, and there is little guidance on the best treatment choices. In this article, we describe treatment via PFC for an adherent FVNCC cyst.
神经囊虫病(NCC)是一种感染性寄生虫病,常发生于有 NCC 流行地区移民或旅行史的患者。第四脑室囊虫病的囊肿带来了独特的治疗挑战,因为对于最佳治疗方法几乎没有共识。本病例研究描述了一名第四脑室神经囊虫病(FVNCC)患者的治疗情况,检查了治疗决策,并提供了后颅窝开颅术(PFC)切除退行性囊肿的视频。
患者出现头痛、头晕、恶心和记忆力减退。磁共振成像发现第四脑室囊肿符合 NCC 的表现,血清酶联免疫吸附试验(ELISA)确诊了该诊断。采用 PFC 切除囊肿,随后进行抗寄生虫治疗和皮质类固醇治疗。术后 9 个月症状缓解。
对于孤立的第四脑室囊肿,已经提出了几种治疗方法,包括药物治疗、脑室-腹腔分流术、内镜下切除和 PFC。治疗决策复杂,对于最佳治疗选择几乎没有指导。在本文中,我们描述了通过 PFC 治疗粘连性 FVNCC 囊肿的情况。