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经 Telovelar 入路和水分离技术切除脑室内多发性神经囊尾蚴病

Racemose Fourth Ventricle Neurocysticercosis Excision Through Telovelar Approach and Hydrodissection.

机构信息

Department of Neurosurgery, University Hospital 12 de Octubre, Madrid, Spain.

Department of Neurosurgery, University Hospital 12 de Octubre, Madrid, Spain.

出版信息

World Neurosurg. 2022 Sep;165:91. doi: 10.1016/j.wneu.2022.06.043. Epub 2022 Jun 16.

Abstract

Intraventricular neurocysticercosis is associated with more severe complications and a worse overall outcome. Fourth ventricle neurocysticercosis (FVNCC) often presents with cerebrospinal fluid obstruction and hydrocephalus by means of direct mechanical occlusion of ventricular outlets by the cysts or due to an ependymal inflammatory response. Unfortunately, there is little consensus on the optimal management for FVNCC. If possible, surgical removal of cysticerci rather than medical therapy and/or shunt surgery is recommended. Endoscopic removal of cysts is described to be an effective treatment modality. However, endoscopic removal of inflamed or adherent ventricular cysticerci is associated with increased risk of complications. Although microdissection through a posterior fossa telovelar approach is a valid method for FVNCC, scarce reports describe the therapeutic decision making and provide a surgical video of adherent FVNCC cyst resection. Video 1 shows a 40-year-old female born in Honduras who presented with progressive headache. Computed tomography revealed ventriculomegaly and transependymal flow. Magnetic resonance imaging demonstrated obstructive hydrocephalus secondary to a multiloculated cystic mass within the fourth ventricle. According to the diagnostic criteria, probable racemose FVNCC was suspected. Magnetic resonance imaging raised suspicion that the cysts could be densely adherent to surrounding structures, precluding endoscopic removal. We performed a combined microscopic and endoscopic approach, which permitted removal of the cysts through a telovelar approach and hydrodissection technique without damaging nearby structures and treatment of the associated hydrocephalus through an endoscopic third ventriculostomy, allowing complete resolution of symptoms and avoidance of cerebrospinal fluid shunting.

摘要

脑室囊虫病与更严重的并发症和更差的整体预后相关。第四脑室囊虫病(FVNCC)常因囊肿直接机械阻塞脑室出口或因室管膜炎症反应而导致脑脊液阻塞和脑积水。不幸的是,对于 FVNCC 的最佳治疗方法尚未达成共识。如果可能,建议通过手术切除囊尾蚴,而不是药物治疗和/或分流手术。已经描述了内镜切除囊肿是一种有效的治疗方式。然而,内镜切除发炎或粘连的脑室囊尾蚴与并发症风险增加相关。虽然通过后颅窝经穹窿间入路进行显微解剖是治疗 FVNCC 的有效方法,但很少有报道描述治疗决策,并提供粘连性 FVNCC 囊肿切除的手术视频。视频 1 显示了一位 40 岁的女性,出生于洪都拉斯,她因进行性头痛就诊。计算机断层扫描显示脑室扩大和室管膜下分流。磁共振成像显示第四脑室多房囊性肿块导致阻塞性脑积水。根据诊断标准,怀疑为可能的脑叶状 FVNCC。磁共振成像提示囊肿可能与周围结构紧密粘连,不适合内镜切除。我们采用了显微镜和内镜联合入路,通过穹窿间入路和水分离技术可以安全地切除囊肿,而不会损伤附近结构,并通过内镜第三脑室造口术治疗相关的脑积水,使症状完全缓解,避免了脑脊液分流。

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