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泰国外科重症监护病房(Thai-SICU)72小时内再入院研究:特征与结局

Re-Admission within 72 Hours in Thai Surgical Intensive Care Units (Thai-SICU) Study: Characteristics, and Outcomes.

作者信息

Poopipatpab Sujaree, Teeratchanan Tanawadee, Chittawatanarat Kaweesak, Trongtrakul Konlawij

出版信息

J Med Assoc Thai. 2016 Sep;99 Suppl 6:S23-S30.

Abstract

OBJECTIVE

To identify incidence, characteristics and outcomes of patients who were re-admitted to surgical intensive care units (SICUs).

MATERIAL AND METHOD

Multicenter prospective cohort study conducted in 9 university-affiliated surgical ICUs in Thailand (THAI-SICU study) from April 2011 to January 2013.

RESULTS

A total of 144 patients (3.1%) re-admitted to our surgical ICUs from 4,652 cases were recruited. Re-admission baseline characteristics were advanced age (mean = 71 years), low body mass index, and higher APACHE-II and SOFA score within 24 hours of first ICU admission. Many significant comorbidities were found in the re-admission group, including: hypertension, cardiovascular diseases, and respiratory diseases. ICU mortality and hospital mortality were higher in readmission group than those in the non re-admission group (20.1% vs. 9.3%, p<0.001 and 27.8% vs. 11.3%, p<0.001, respectively). The relative risk ratio for mortality between re-admission and non re-admission in ICU was 2.17 times and in hospital mortality was 2.46 times greater. Independent potential risk factors for re-admission were age (OR 1.028, 95% CI 1.001-1.051), emergency surgical intervention (OR 1.978, 95% CI 1.027-3.813), transfer back from general wards (OR 4.175, 95% CI 2.020-8.628), and respiratory failure needing mechanical ventilation (OR 2.167, 95% CI 1.065-4.407).

CONCLUSION

Re-admission was found in 3.1% of cases in our surgical ICUs. This problem is associated with significantly higher ICU and hospital mortality. Risk factors of re-admission were patient age, emergency surgery, re-admission from general wards, and need for respiratory support.

摘要

目的

确定再次入住外科重症监护病房(SICU)患者的发生率、特征及转归。

材料与方法

2011年4月至2013年1月在泰国9家大学附属医院的外科ICU进行的多中心前瞻性队列研究(泰国SICU研究)。

结果

从4652例患者中,共有144例(3.1%)再次入住我们的外科ICU。再次入院的基线特征为高龄(平均71岁)、低体重指数,以及首次入住ICU后24小时内较高的急性生理与慢性健康状况评分系统II(APACHE-II)和序贯器官衰竭评估(SOFA)评分。再次入院组存在许多显著的合并症,包括高血压、心血管疾病和呼吸系统疾病。再次入院组的ICU死亡率和医院死亡率高于未再次入院组(分别为20.1%对9.3%,p<0.001;27.8%对11.3%,p<0.001)。再次入院与未再次入院患者在ICU的死亡相对风险比为2.17倍,在医院死亡的相对风险比为2.46倍。再次入院的独立潜在风险因素为年龄(比值比[OR]1.028,95%置信区间[CI]1.001 - 1.051)、急诊手术干预(OR 1.978,95% CI 1.027 - 3.813)、从普通病房转回(OR 4.175,95% CI 2.020 - 8.628)以及需要机械通气的呼吸衰竭(OR 2.167,95% CI 1.065 - 4.407)。

结论

我们外科ICU中3.1%的病例存在再次入院情况。这一问题与显著更高的ICU和医院死亡率相关。再次入院的风险因素为患者年龄、急诊手术、从普通病房再次入院以及需要呼吸支持。

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