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泰国外科重症监护病房气胸的发病率、特征及转归(泰国外科重症监护病房研究)

The Incidence, Characteristics and Outcomes of Pneumothorax in Thai Surgical Intensive Care Units (Thai-SICU Study).

作者信息

Poopipatpab Sujaree, Trongtrakul Konlawij, Pathonsamit Chompunoot, Siraklow Siriporn, Limphunudom Ploynapas, Chittawatanarat Kaweesak

出版信息

J Med Assoc Thai. 2016 Sep;99 Suppl 6:S128-S135.

PMID:29906370
Abstract

OBJECTIVE

To identify incidence, characteristics, and outcomes of pneumothorax among patients who specifically stayed in surgical intensive care units (SICUs).

MATERIAL AND METHOD

This was a multicenter prospective cohort study conducted in 9 University-affiliated SICUs in Thailand. Incidence of pneumothorax and its outcomes were evaluated from April 2011 to January 2013.

RESULTS

4,652 patients who were admitted to SICU were enrolled. The incidence of pneumothorax was 0.5% (25 cases) in our study. Significant characteristics were found in the pneumothorax group, including: lower BMI, underlying malignancy and COPD, higher APACHE-II and SOFA score within 24 hours of first ICU admission, pulmonary infiltration pattern of chest imaging and usage of mechanical ventilation. In terms of outcome, there were higher SICU mortality and 28-day hospital mortality in pneumothorax than non-pneumothorax patients at 28.0% vs. 9.6%, p = 0.002 and at 44.0% vs. 13.6%, p<0.001, respectively.

CONCLUSION

Patients admitted to surgical intensive care units who developed pneumothorax had higher risk of intensive care unit mortality and 28-day hospital mortality than non-pneumothorax patients, as well as a longer intensive care unit and hospital length of stays.

摘要

目的

确定专门入住外科重症监护病房(SICU)的患者气胸的发生率、特征及预后。

材料与方法

这是一项在泰国9所大学附属医院的SICU进行的多中心前瞻性队列研究。对2011年4月至2013年1月期间气胸的发生率及其预后进行评估。

结果

纳入了4652例入住SICU的患者。本研究中气胸的发生率为0.5%(25例)。气胸组存在显著特征,包括:较低的体重指数、潜在恶性肿瘤和慢性阻塞性肺疾病、首次入住ICU后24小时内较高的急性生理与慢性健康状况评分系统II(APACHE-II)和序贯器官衰竭评估(SOFA)评分、胸部影像学的肺部浸润模式以及机械通气的使用情况。在预后方面,气胸患者的SICU死亡率和28天医院死亡率高于非气胸患者,分别为28.0%对9.6%,p = 0.002;以及44.0%对13.6%,p<0.001。

结论

入住外科重症监护病房且发生气胸的患者,其重症监护病房死亡率和28天医院死亡率高于非气胸患者,同时重症监护病房和住院时间更长。

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