Br J Pharmacol. 2018 Jul;175(13):2712. doi: 10.1111/bph.14349. Epub 2018 May 23.
The above article, published by the British Journal of Pharmacology in October 2015 (https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13259), has been retracted by agreement between the authors, the journal Editor in Chief and John Wiley & Sons Limited. The retraction has been agreed owing to the discovery of errors in the chemical structure of the synthetic compounds generated. The corrected structure is now available in the article PF-06526290 can both enhance and inhibit conduction through voltage gated sodium channels by L Wang, SG Zellmer, DM Printzenhoff and NA Castle, 2018, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14338. Reference Wang L, Zellmer SG, Printzenhoff DM, Castle NA (2015). Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. Br J Pharmacol 172: 4905-4918. https://doi.org/10.1111/bph.13259.
上述文章由《英国药理学期刊》于2015年10月发表(https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13259),经作者、期刊主编与约翰·威利父子有限公司协商后予以撤回。撤回的原因是发现所生成的合成化合物化学结构存在错误。修正后的结构可在文章《PF-06526290可增强和抑制电压门控钠通道传导》中获取,作者为L·王、SG·泽尔默、DM·普林曾霍夫和NA·卡斯尔,发表于2018年(https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14338)。参考文献:王L、泽尔默SG、普林曾霍夫DM、卡斯尔NA(2015年)。向一种小分子钠通道抑制剂添加单个甲基可引入一种新的门控调节模式。《英国药理学期刊》172: 4905 - 4918。https://doi.org/10.1111/bph.13259 。