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评估骨盆骨折手术患者的静脉血栓栓塞并发症。

Evaluation of venous thromboembolic complications in patients operated on for pelvic fracture.

机构信息

Service de médecine vasculaire, groupe hospitalier Paris Saint-Joseph, 75014 Paris, France.

Service de chirurgie orthopédique, groupe hospitalier Paris Saint-Joseph, 75014 Paris, France.

出版信息

Orthop Traumatol Surg Res. 2018 Oct;104(6):917-921. doi: 10.1016/j.otsr.2018.04.017. Epub 2018 Jun 12.

Abstract

INTRODUCTION

Fractures of the pelvis (acetabulum and pelvic ring) are complex in both radiological diagnosis and therapeutic management. They show high-risk of thrombosis, with variable rates of venous thromboembolic complications in the literature, ranging from 10% to 50%, with 0.5-10% risk of fatal pulmonary embolism. The objective of the present study was to determine the rate of venous thromboembolic events in a consecutive cohort of pelvic fracture and to attempt to identify thromboembolic risk factors in this population.

MATERIAL AND METHOD

The study was based on a continuous retrospective series of 120 patients operated on between January 2015 and January 2017. Standard demographic data, clinical and diagnostic data for the fracture and the surgical approach were collected. Risk factors for venous thrombotic episodes were identified on Greenfield Risk Assessment Profile items (age, BMI, cancer, history of venous thromboembolism, surgery time, transfusion, femoral venous catheter, associated fracture) to define groups with high or low thrombotic risk.

RESULTS

There was a 5% rate of venous thromboembolic events, and 2.5% of pulmonary embolism including 1 causing intraoperative death. The Greenfield score usually applied in surgery to assess venous thromboembolic risk did not seem relevant in this population already at high-risk of venous thromboembolism. No additional independent risk factors were identified.

CONCLUSION

This is the largest cohort focusing on thromboembolic risk in pelvic fracture. The results refine rates reported in the literature. A prospective study, currently underway, should highlight risk factors so as better to prevent these complications.

摘要

引言

骨盆(髋臼和骨盆环)骨折在放射诊断和治疗管理方面都很复杂。它们存在高血栓形成风险,文献中静脉血栓栓塞并发症的发生率变化范围为 10%至 50%,其中 0.5%至 10%有致命性肺栓塞的风险。本研究的目的是确定连续骨盆骨折患者群中静脉血栓栓塞事件的发生率,并尝试确定该人群中的血栓栓塞危险因素。

材料和方法

本研究基于 2015 年 1 月至 2017 年 1 月期间连续接受手术治疗的 120 例患者的连续回顾性系列。收集了标准的人口统计学数据、骨折的临床和诊断数据以及手术方法。根据 Greenfield 风险评估表项目(年龄、BMI、癌症、静脉血栓栓塞史、手术时间、输血、股静脉导管、合并骨折)确定静脉血栓形成事件的危险因素,以定义高或低血栓形成风险组。

结果

发生静脉血栓栓塞事件的比例为 5%,其中肺栓塞的比例为 2.5%,包括 1 例术中死亡。Greenfield 评分通常用于手术中评估静脉血栓栓塞风险,但在已经处于高静脉血栓栓塞风险的人群中似乎并不相关。未确定其他独立的危险因素。

结论

这是最大的一组专注于骨盆骨折血栓栓塞风险的队列。结果细化了文献中的报告率。目前正在进行的前瞻性研究应突出风险因素,以便更好地预防这些并发症。

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