Barba-Navarrete D M, Moreno-Páramo D, Corona-Montes V E, Tapia-López L E, Montiel-Delgado E
Servicio de Retina, Hospital General de México, Ciudad de México, México.
Servicio de Retina, Hospital General de México, Ciudad de México, México.
Arch Soc Esp Oftalmol (Engl Ed). 2018 Sep;93(9):417-422. doi: 10.1016/j.oftal.2018.05.004. Epub 2018 Jun 12.
The curing of a testicular tumour is currently feasible in more than 95% of patients, and in 80% of those with metastases. Until now, there has been no study or series of cases that describe the ocular changes of the posterior segment associated with testicular cancer.
To evaluate patients with a diagnosis of testicular cancer in order to determine the presence of changes in the posterior segment and the relationship to the stage.
An observational, cross-sectional, and descriptive study was conducted on 21 male patients (42 eyes) with a diagnosis of testicular cancer. Age, histological type, time of evolution, stage, treatment, and comorbidities were recorded, as well as visual acuity measurement (LogMAR), biomicroscopy of the anterior segment, and photographic records of the posterior pole and peripheral retina.
The mean age was 29 years (18-43 years). All (100%) of the patients were treated surgically. The most frequent histological type was classic seminoma (42.8%), followed by the mixed germinal tumour (38.0%). At the time of evaluation, 42.8% of patients had a stage II, and 23.8% had distant metastasis. The changes in the posterior segment were: vascular tortuosity (14.2%), retinopathy associated with cancer (9.5%), choroidal metastasis (9.5%), pigmentary changes of the retinal pigment epithelium (9.5%), and retinal metastasis (4.7%).
It is possible to find changes at the level of retinal pigment epithelium, as well as vascular tortuosity, retinopathy associated with cancer, and choroidal and/or retina metastases.
目前,超过95%的睾丸肿瘤患者以及80%有转移的患者的疾病可以治愈。到目前为止,尚无研究或系列病例描述与睾丸癌相关的眼后段变化。
评估诊断为睾丸癌的患者,以确定眼后段是否存在变化以及与分期的关系。
对21例诊断为睾丸癌的男性患者(42只眼)进行了一项观察性、横断面描述性研究。记录患者的年龄、组织学类型、病程、分期、治疗情况和合并症,以及视力测量(LogMAR)、前段生物显微镜检查和后极及周边视网膜的摄影记录。
平均年龄为29岁(18 - 43岁)。所有患者(100%)均接受了手术治疗。最常见的组织学类型是经典精原细胞瘤(42.8%),其次是混合性生殖细胞瘤(38.0%)。在评估时,42.8%的患者处于II期,23.8%有远处转移。眼后段的变化包括:血管迂曲(14.2%)、癌相关性视网膜病变(疫9.5%)、脉络膜转移(9.5%)、视网膜色素上皮色素改变(9.5%)和视网膜转移(4.7%)。
在视网膜色素上皮水平以及血管迂曲、癌相关性视网膜病变和脉络膜及/或视网膜转移方面有可能发现变化。