Department of Nursing, First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China (mainland).
College of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, Hebei, China (mainland).
Med Sci Monit. 2018 Jun 16;24:4101-4112. doi: 10.12659/MSM.906666.
BACKGROUND There is a great need for a quality of sexual life questionnaire (QVS) in breast cancer survivors (BCSs) based on the Chinese social culture since the imported tools lack localization verification. To develop a QVS in BCSs and determine its validity and reliability. MATERIAL AND METHODS In the qualitative study, a total of 21 BCSs were interviewed by purposive sampling and snowball sampling; and in the quantitative study, a total of 249 BCSs, who were admitted and received outpatient follow-up, were investigated. Regarding construct validity, factor analysis was performed. The female sexual function index (FSFI), self-rating depression scale (SDS), and Locke-Wallace marital adjustment test (LWMAT) were used to evaluate criterion validity. Cronbach's alpha coefficient was used as an index of internal consistency. To evaluate test-retest reliability, 50 patients were re-evaluated after 1 week. RESULTS We put 28 items in the factor analysis model: (1) 5 factors were extracted by exploratory factor analysis (EFA), with a cumulative contribution of 60.37%; (2) the confirmatory factor analysis (CFA) showed that the path coefficients among the factors were all above 0.5, and the standardized load coefficients of the most items were above 0.5; (3) the Cronbach's alpha coefficient was 0.929 for the overall questionnaire, and ranged from 0.571 to 0.869 for the 5 factors; (4) the correlation coefficients between the overall questionnaire and the FSFI, SDS, and LWMAT were 0.582, -0.456 and 0.515, respectively (P<0.01); and (5) the test-retest correlation coefficient was 0.816, and the split-half-reliability coefficient was 0.899. CONCLUSIONS The QVS in BCSs has good reliability and validity, and can be used to assess the quality of sexual life among BCSs in Mainland China.
由于进口工具缺乏本地化验证，因此乳腺癌幸存者（BCS）非常需要基于中国社会文化的生活质量问卷（QVS）。本研究旨在研制中文版乳腺癌幸存者性生活质量问卷并评价其信度和效度。
采用目的抽样和滚雪球抽样法对 21 例 BCS 进行定性研究；采用便利抽样法对 249 例接受门诊随访的 BCS 进行定量研究。采用因子分析法进行结构效度评价，采用女性性功能指数（FSFI）、抑郁自评量表（SDS）、Locke-Wallace 婚姻调整测试（LWMAT）评价效标效度，采用克朗巴赫α系数评价内部一致性，采用重测信度评价 50 例患者 1 周后的重测信度。
共纳入 28 个条目，探索性因子分析提取 5 个公因子，累计贡献率为 60.37%；验证性因子分析显示各因子间路径系数均大于 0.5，大部分项目标准化负荷系数大于 0.5；总量表 Cronbach α系数为 0.929，5 个维度的 Cronbach α系数为 0.571～0.869；总量表与 FSFI、SDS、LWMAT 的相关系数分别为 0.582、-0.456、0.515（P<0.01）；重测信度为 0.816，分半信度为 0.899。
中文版乳腺癌幸存者性生活质量问卷具有较好的信度和效度，可用于评估中国大陆地区 BCS 的性生活质量。
