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机器人子宫肌瘤切除术中手动粉碎术与电动粉碎术的比较。

Manual morcellation compared to power morcellation during robotic myomectomy.

作者信息

Sanderson Derrick J, Sanderson Rohnn, Cleason Dana, Seaman Catherine, Ghomi Ali

机构信息

Department of Obstetrics and Gynecology, Sisters of Charity Hospital, 2157 Main Street, Buffalo, NY, 14214, USA.

W.H. Thompson School of Business, Brescia University, Owensboro, KY, USA.

出版信息

J Robot Surg. 2019 Apr;13(2):209-214. doi: 10.1007/s11701-018-0837-y. Epub 2018 Jun 15.

Abstract

Clinical practice has drastically changed following the 2014 U.S. Food and Drug Administration (FDA) warning statement regarding power morcellation during laparoscopic hysterectomy and myomectomy. Despite investigation into alternative tissue extraction techniques, there remain a paucity of data associated with contained manual morcellation techniques. The goal of this study was to investigate the associated perioperative outcomes of contained manual morcellation compared to power morcellation in women undergoing robotic myomectomy. Performing manual morcellation (n = 38) resulted in a 21-min decrease in mean operative time (105.4 ± 42.2 vs 126.1 ± 44.1 min, p = 0.02) compared to power morcellation (n = 62). Women were younger (33 vs 36 years, p = 0.03) in the manual morcellation group, with all other patient demographics being similar. Median specimen weight (82 vs 104 g, p = 0.13), number of fibroids removed (2 vs 1, p = 0.16), estimated blood loss (10 vs 50 mL, p = 0.25), and post-operative morphine equivalents administered (5.57 ± 4.57 vs 5.29 ± 4.39, p = 0.76) were similar. The same-day discharge rate was not significantly different between the groups (86 vs 90%, p = 0.74). Linear regression modeling identified specimen weight, number of fibroids removed, and use of power morcellation as significant contributors to surgical time. Contained manual morcellation during robotic myomectomy is associated with a significant decrease in surgical time when compared to power morcellation, with similar post-operative narcotic administration and length of stay.

摘要

2014年美国食品药品监督管理局(FDA)发布关于腹腔镜子宫切除术和子宫肌瘤切除术中使用动力粉碎术的警示声明后,临床实践发生了巨大变化。尽管对替代组织提取技术进行了研究,但关于封闭式手动粉碎技术的数据仍然很少。本研究的目的是调查在接受机器人子宫肌瘤切除术的女性中,封闭式手动粉碎术与动力粉碎术相比的围手术期相关结局。与使用动力粉碎术(n = 62)相比,进行手动粉碎术(n = 38)使平均手术时间减少了21分钟(105.4±42.2 vs 126.1±44.1分钟,p = 0.02)。手动粉碎术组的女性更年轻(33岁 vs 36岁,p = 0.03),其他所有患者人口统计学特征相似。中位标本重量(82 g vs 104 g,p = 0.13)、切除的肌瘤数量(2个 vs 1个,p = 0.16)、估计失血量(10 mL vs 50 mL,p = 0.25)以及术后给予的吗啡当量(5.57±4.57 vs 5.29±4.39,p = 0.76)相似。两组的当日出院率无显著差异(86% vs 90%,p = 0.74)。线性回归模型确定标本重量、切除的肌瘤数量和动力粉碎术的使用是手术时间的重要影响因素。与动力粉碎术相比,机器人子宫肌瘤切除术中的封闭式手动粉碎术可显著缩短手术时间,术后麻醉剂使用和住院时间相似。

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