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腹腔镜子宫切除术和子宫肌瘤切除术时碎解技术的比较

Comparison of Morcellation Techniques at the Time of Laparoscopic Hysterectomy and Myomectomy.

作者信息

Meurs Elsemieke A I M, Brito Luiz Gustavo, Ajao Mobolaji O, Goggins Emily R, Vitonis Allison F, Einarsson Jon I, Cohen Sarah L

机构信息

Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

J Minim Invasive Gynecol. 2017 Jul-Aug;24(5):843-849. doi: 10.1016/j.jmig.2017.04.023. Epub 2017 May 5.

Abstract

STUDY OBJECTIVE

To compare perioperative outcomes associated with the use of 3 techniques for tissue removal at the time of laparoscopic hysterectomy and myomectomy.

DESIGN

A retrospective cohort study (Canadian Task Force classification II-2).

SETTING

An academic hospital in Boston, MA.

PATIENTS

Women who underwent a laparoscopic or robot-assisted laparoscopic hysterectomy or myomectomy involving tissue morcellation in 2014.

INTERVENTIONS

One of 3 morcellation techniques: electronic power morcellation (PM), manual vaginal morcellation via the vagina (VM), or manual morcellation via minilaparotomy (ML).

MEASUREMENTS AND MAIN RESULTS

Of the 297 cases included in this study (137 myomectomies, 62 total laparoscopic hysterectomies, and 98 laparoscopic supracervical hysterectomies), 96% of the cases were performed by fellowship-trained surgeons using conventional laparoscopy. Containment bags were used at the time of tissue extraction in 77% of the cases. Baseline characteristics and perioperative outcomes were similar in all groups. In hysterectomy cases, the average specimen size was largest in the ML group (591 ± 419 g in the ML group compared with 368 ± 293 g in the PM group and 449 ± 175 g in the VM group, p = .0009). After multivariate regression, no significant difference was found in blood loss, length of stay, or complications. The operative time was shorter in the PM group compared with the ML group by 16 minutes (mean = 140 minutes [95% confidence interval, 130-149 minutes] compared with 156 [95% confidence interval, 146-167], p = .02); this association remained significant once additionally adjusting for the use or nonuse of containment bags (p = .05).

CONCLUSION

We did not detect a significant difference between the 3 morcellation techniques when comparing the perioperative complications although the longest operative times were noted for the minilaparotomy approach. All 3 morcellation techniques represent viable options for tissue extraction at the time of minimally invasive surgery.

摘要

研究目的

比较腹腔镜子宫切除术和子宫肌瘤剔除术时使用3种组织切除技术的围手术期结局。

设计

一项回顾性队列研究(加拿大工作组分类II-2)。

地点

马萨诸塞州波士顿的一家学术医院。

患者

2014年接受腹腔镜或机器人辅助腹腔镜子宫切除术或子宫肌瘤剔除术且涉及组织粉碎术的女性。

干预措施

3种粉碎术技术之一:电动粉碎术(PM)、经阴道手动粉碎术(VM)或经迷你剖腹术手动粉碎术(ML)。

测量指标及主要结果

本研究纳入297例病例(137例子宫肌瘤剔除术、62例全腹腔镜子宫切除术和98例腹腔镜次全子宫切除术),96%的病例由经过专科培训的外科医生采用传统腹腔镜技术完成。77%的病例在组织取出时使用了 containment bags。所有组的基线特征和围手术期结局相似。在子宫切除术病例中,ML组的平均标本重量最大(ML组为591±419g,PM组为368±293g,VM组为449±175g,p = 0.0009)。多因素回归分析后,在失血量、住院时间或并发症方面未发现显著差异。PM组的手术时间比ML组短16分钟(平均分别为140分钟[95%置信区间,130 - 149分钟]和156分钟[95%置信区间,146 - 167分钟],p = 0.02);在额外调整是否使用containment bags后,这种关联仍然显著(p = 0.05)。

结论

尽管迷你剖腹术方法的手术时间最长,但在比较围手术期并发症时,我们未发现3种粉碎术技术之间存在显著差异。所有3种粉碎术技术都是微创手术时组织取出的可行选择。

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