巴基斯坦 HIV 阳性男性静脉吸毒者的抗逆转录病毒治疗依从性。
Adherence to antiretroviral therapy in HIV-positive, male intravenous drug users in Pakistan.
机构信息
School of Public Health, Dow University of Health Sciences, Karachi, Pakistan.
Deparment of Community Medicine, Dow University of Health Sciences, Karachi, Pakistans.
出版信息
East Mediterr Health J. 2018 Jun 10;24(3):237-242. doi: 10.26719/2018.24.3.237.
BACKGROUND
Human immunodeficiency virus (HIV) is fifth leading cause of mortality and disability among infectious diseases worldwide. HIV burden is increasing annually and compliance with antiretroviral therapy (ART) is low among intravenous drug users, especially in developing countries.
AIM
To determine the adherence level to ART among HIV-positive intravenous drug users in Karachi Pakistan.
METHODS
A cross-sectional study was conducted in 2015. A pretested questionnaire was administered to 375 of 3000 people who inject drugs, registered at the Civil Hospital in Karachi, Pakistan.
RESULTS
The mean age was 30 years, 181 were married, 179 were illiterate and 287 had income < 5000 rupees per month. Only 63 patients were adherent to ART and 343 were alcoholics. Nonadherence was greater in patients who were single and did not have children. The most common reason for missing ART was that they simply forgot to take the tablets.
CONCLUSION
We conclude that adherence to ART among intravenous drug users was low. Family cohesion and support were essential to maintain adherence to ART.
背景
在全球传染病中，人类免疫缺陷病毒（HIV）是导致死亡和残疾的第五大原因。HIV 负担每年都在增加，静脉注射吸毒者（IDUs），特别是在发展中国家，对艾滋病抗病毒治疗（ART）的依从性较低。
目的
确定巴基斯坦卡拉奇 HIV 阳性静脉吸毒者对 ART 的依从水平。
方法
2015 年进行了一项横断面研究。在巴基斯坦卡拉奇市立医院登记的 3000 名注射吸毒者中，对 375 名进行了预测试问卷调查。
结果
平均年龄为 30 岁，181 人已婚，179 人是文盲，287 人月收入低于 5000 卢比。只有 63 名患者坚持服用 ART，343 名患者酗酒。单身且没有孩子的患者不依从的比例更高。错过 ART 的最常见原因是他们只是忘了服用片剂。
结论
我们得出结论，静脉吸毒者对 ART 的依从性较低。家庭凝聚力和支持对于保持对 ART 的依从性至关重要。
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