Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China.
Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China.
Ecotoxicol Environ Saf. 2018 Oct;161:420-429. doi: 10.1016/j.ecoenv.2018.05.074. Epub 2018 Jun 13.
Flonicamid, a novel selective systemic pesticide, can effectively control a broad range of insect pests. However, the dissipation behaviors and the terminal residues of flonicamid and its metabolites in some crops and soils remain unclear. Herein, an easy, sensitive and reliable method using a modified QuEChERS extraction coupled with LC-MS/MS for the simultaneous analysis of flonicamid and its metabolites in cabbage and soil was developed. Based on this method, the dissipation behaviors of flonicamid and its metabolites as well as their persistence in cabbage and soil during harvest were investigated. Flonicamid degraded rapidly, and the half-lives of flonicamid only and total residues (the sum of flonicamid and its metabolites) were 1.49-4.59 and 1.97-4.99 days in cabbage, and 2.12-7.97 and 2.04-7.62 days in soil, respectively. When 50% flonicamid WG was sprayed once or twice at the recommended dose and 1.5-fold the recommended dose, the highest residues of total flonicamid in cabbage and soil from different pre-harvest intervals (3, 7 and 14 days) were 0.070 and 0.054 mg kg, respectively. The risk quotient (RQ) of flonicamid based on the consumption data from China was below 16.84%, indicating that the use of flonicamid is non-hazardous to humans. These results could not only guide the safe and responsible use of flonicamid in agriculture but also help the Chinese government establish the maximum residue level (MRL) for flonicamid in cabbage.
氟啶虫酰胺是一种新型选择性内吸杀虫剂，能有效防治多种害虫。然而，氟啶虫酰胺及其代谢物在一些作物和土壤中的消解行为和最终残留仍不清楚。本研究建立了一种采用改良 QuEChERS 提取与 LC-MS/MS 相结合的简单、灵敏、可靠的方法，用于同时分析甘蓝和土壤中的氟啶虫酰胺及其代谢物。在此方法基础上，研究了氟啶虫酰胺及其代谢物在甘蓝和土壤中的消解动态和残留稳定性。氟啶虫酰胺降解迅速，氟啶虫酰胺及其总残留（氟啶虫酰胺及其代谢物之和）在甘蓝和土壤中的半衰期分别为 1.49-4.59 和 1.97-4.99 天，以及 2.12-7.97 和 2.04-7.62 天。当 50%氟啶虫酰胺水分散粒剂按推荐剂量和推荐剂量的 1.5 倍各喷雾一次和两次时，不同施药间隔（3、7 和 14 天）收获的甘蓝和土壤中总氟啶虫酰胺的最高残留量分别为 0.070 和 0.054 mg/kg。基于中国的消费量数据，氟啶虫酰胺的风险商数（RQ）低于 16.84%，表明氟啶虫酰胺的使用对人类没有危害。这些结果不仅可以指导农业中氟啶虫酰胺的安全合理使用，还可以帮助中国政府制定氟啶虫酰胺在甘蓝中的最大残留限量（MRL）。
