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皮肤病学中的微生物组。

The microbiome in dermatology.

作者信息

Musthaq Shenara, Mazuy Anna, Jakus Jeannette

机构信息

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, NY.

Early Clinical Evaluation Department, Galderma-Nestlé Skin Health R&D, Les Templiers, Sophia Antipolis, France.

出版信息

Clin Dermatol. 2018 May-Jun;36(3):390-398. doi: 10.1016/j.clindermatol.2018.03.012. Epub 2018 Mar 10.

Abstract

The skin supports a delicate ecosystem of microbial elements. Although the skin typically acts as a barrier, these microbes interact with the internal body environment and imbalances from the "healthy" state that have been linked to several dermatologic diseases. Understanding the changes in microbial flora in disease states allows for the potential to treat by restoring equilibrium. With the rising popularity of holistic and natural consumerism, prebiotics, probiotics, symbiotic, and other therapies are under study to find alternative treatments to these skin disorders through manipulation or supplementation of the microbiome.

摘要

皮肤维持着一个由微生物组成的微妙生态系统。尽管皮肤通常起到屏障作用,但这些微生物会与人体内部环境相互作用,而与“健康”状态的失衡已被认为与多种皮肤病有关。了解疾病状态下微生物群落的变化有助于通过恢复平衡来进行潜在治疗。随着整体和自然消费主义的日益流行,人们正在研究益生元、益生菌、共生体及其他疗法,以期通过操控或补充微生物群来找到这些皮肤疾病的替代治疗方法。

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