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急诊科儿童和青少年头痛患者神经影像学的应用。

Emergency Department Use of Neuroimaging in Children and Adolescents Presenting with Headache.

机构信息

Department of Emergency Medicine, Mayo Clinic, Rochester, MN; Pediatric Emergency Medicine, Children's Minnesota, Minneapolis, MN.

Sage Therapeutics, Cambridge, MA.

出版信息

J Pediatr. 2018 Oct;201:196-201. doi: 10.1016/j.jpeds.2018.05.023. Epub 2018 Jun 14.

Abstract

OBJECTIVES

To evaluate emergency department use and outcomes of neuroimaging for headache in a free-standing children's hospital system.

STUDY DESIGN

We prospectively enrolled children aged 6-18 years who presented to the emergency department with a chief complaint of headache from September 2015 to September 2016. Standardized data collection was performed in real time, including telephone follow-up as needed, and imaging outcome was determined through a chart review. Using multivariable logistic regression, we estimated the associations between clinically important patient characteristics and neuroimaging.

RESULTS

Of 294 enrolled patients, 53 (18%) underwent neuroimaging (computed tomography or magnetic resonance imaging) and 2 (0.7%) had clinically important intracranial findings. Presenting with abnormal neurologic examination findings (OR, 11.55; 95% CI, 3.24-41.22), no history of similar headaches (OR, 2.13; 95% CI, 1.08-4.18), and white race (OR, 3.04; 95% CI, 1.51-6.12) were significantly associated with an increased odds of undergoing imaging in multivariable regression models.

CONCLUSIONS

Our observed emergency department imaging rate was 26.5 times higher than our positive result rate, suggesting there is room to decrease unnecessary neuroimaging. Associations for abnormal examination and new headache type are consistent with the American Academy of Neurology clinical imaging recommendations. The increased odds of imaging white patients suggests bias that should be addressed. The low rate of positive findings supports the need for an evidence-based clinical decision tool for neuroimaging in the acute care setting.

摘要

目的

评估一家独立儿童医院系统中神经影像学在头痛急诊中的应用及结果。

研究设计

我们前瞻性纳入了 2015 年 9 月至 2016 年 9 月因头痛就诊于急诊的年龄在 6-18 岁的儿童。实时进行标准化数据采集,包括必要时进行电话随访,并通过病历回顾确定影像学结果。使用多变量逻辑回归,我们估计了有临床意义的患者特征与神经影像学之间的关联。

结果

在 294 名入组患者中,53 名(18%)接受了神经影像学(计算机断层扫描或磁共振成像)检查,2 名(0.7%)有临床意义的颅内发现。存在异常神经系统检查结果(OR,11.55;95%CI,3.24-41.22)、无类似头痛病史(OR,2.13;95%CI,1.08-4.18)和白人种族(OR,3.04;95%CI,1.51-6.12)与多变量回归模型中影像学检查几率增加显著相关。

结论

我们观察到的急诊科影像学检查率是阳性结果率的 26.5 倍,这表明有减少不必要的神经影像学检查的空间。异常检查和新发头痛类型的关联与美国神经病学学会的临床影像学推荐一致。白人患者影像学检查几率增加表明存在偏见,需要解决。阳性发现率低支持在急性护理环境中开发基于证据的神经影像学临床决策工具的必要性。

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