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初次全髋关节置换术患者何时应进行全血细胞计数检查?

When Should Complete Blood Count Tests Be Performed in Primary Total Hip Arthroplasty Patients?

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.

出版信息

J Arthroplasty. 2018 Oct;33(10):3211-3214. doi: 10.1016/j.arth.2018.05.030. Epub 2018 May 29.

DOI:10.1016/j.arth.2018.05.030
PMID:29908797
Abstract

BACKGROUND

Routine laboratory studies are often obtained following total hip arthroplasty (THA). Moreover, laboratory studies are often continued daily until the patient is discharged regardless of medical management. The purpose of this study was to investigate the use of routine complete blood count (CBC) tests following THA. Secondarily, the purpose was to identify patient factors associated with abnormal postoperative lab values.

METHODS

This retrospective review identified 352 patients who underwent primary THA at a single institution from 2012 to 2014. Preoperative and postoperative CBC values were collected along with demographic data, use of tranexamic acid (TXA), and transfusion rates. Logistic regression models were used to identify factors associated with an abnormal postoperative lab and risk of transfusion.

RESULTS

Of the 352 patients, 54 patients were transfused (15.3%). Patients who underwent transfusion had a significantly lower preoperative hemoglobin (Hb; 12.0 g/dL) compared to patients who did not undergo transfusion (13.5 g/dL; P < .001). Patients who did not receive TXA were 3.7 times more likely to receive a transfusion. No patients received medical intervention based on the outcome of postoperative platelet or white blood counts. A Hb value below 11.94 g/dL for patients who are anemic preoperative or did not receive TXA predicted transfusion after postoperative day 1.

CONCLUSION

Under value-based care models, cost containment while maintaining high-quality patient care is critical. Routine postoperative CBC tests in patients with a normal preoperative Hb who receive TXA do not contribute to actionable information. Patients who are anemic before THA or do not receive TXA should at minimum obtain a CBC on postoperative day 1.

摘要

背景

全髋关节置换术(THA)后通常会进行常规实验室检查。此外,无论医疗管理如何,实验室检查通常会持续进行,直到患者出院。本研究旨在探讨 THA 后常规全血细胞计数(CBC)检查的应用。其次,目的是确定与术后实验室值异常相关的患者因素。

方法

本回顾性研究在一家机构确定了 2012 年至 2014 年期间接受初次 THA 的 352 名患者。收集了术前和术后的 CBC 值以及人口统计学数据、氨甲环酸(TXA)的使用情况和输血率。使用逻辑回归模型确定与术后实验室异常和输血风险相关的因素。

结果

在 352 名患者中,有 54 名患者接受了输血(15.3%)。接受输血的患者术前血红蛋白(Hb)明显低于未输血的患者(12.0g/dL 比 13.5g/dL;P<.001)。未接受 TXA 的患者输血的可能性是未接受 TXA 的患者的 3.7 倍。没有患者根据术后血小板或白细胞计数的结果接受医疗干预。术前贫血或未接受 TXA 的患者术后 Hb 值低于 11.94g/dL,预测术后第 1 天输血。

结论

在基于价值的护理模式下,在保持高质量患者护理的同时控制成本至关重要。对于术前 Hb 值正常且接受 TXA 的患者,常规术后 CBC 检查不会提供有用信息。术前贫血或未接受 TXA 的患者至少应在术后第 1 天进行 CBC 检查。

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