Hannerz Harald, Larsen Ann Dyreborg, Garde Anne Helene
National Research Centre for the Working Environment, Copenhagen, Denmark.
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
BMJ Open. 2018 Jun 15;8(6):e019807. doi: 10.1136/bmjopen-2017-019807.
The aim of the present study was to test if incidences of ischaemic heart disease (IHD) and usage of antihypertensive drugs are independent of weekly working hours (WWH) among full-time employees in Denmark.
Data on WWH from participants of the Danish labour force surveys, 1999-2013, were linked on an individual level to national registers with data on socioeconomic status (SES), industry, emigrations, redeemed prescriptions, hospital contacts and deaths. Participants were followed until the end of 2014 (on average 7.7 years). Poisson regression was used to model incidence rates as a function of WWH. The analyses were controlled for calendar time, time passed since start of follow-up, employment in the healthcare industry, age, sex, SES and night work.
In total, we found 3635 cases of IHD and 20 648 cases of antihypertensive drug usage. The rate ratio of IHD was 0.95 (95% CI 0.85 to 1.06) for 41-48 compared with 32-40 WWH and 1.07 (0.94 to 1.21) for >48 compared with 32-40 WWH. The corresponding rate ratios for antihypertensive drug usage were 0.99 (0.95 to 1.04) and 1.02 (0.97 to 1.08). No statistically significant interactions between WWH and sex, SES and night work, respectively, were found.
In this Danish sample, we did not find any statistically significant association between WWH and IHD or antihypertensive drug usage.
本研究旨在检验丹麦全职员工中缺血性心脏病（IHD）的发病率和降压药物的使用情况是否与每周工作时长（WWH）无关。
1999年至2013年丹麦劳动力调查参与者的WWH数据在个体层面上与国家登记册相链接，登记册包含社会经济地位（SES）、行业、移民、已赎回处方、医院就诊和死亡数据。对参与者进行随访直至2014年底（平均7.7年）。采用泊松回归将发病率建模为WWH的函数。分析中控制了日历时间、随访开始后的时间、医疗行业就业情况、年龄、性别、SES和夜班工作。
我们总共发现3635例IHD病例和20648例降压药物使用病例。与32 - 40小时的WWH相比，41 - 48小时的WWH对应的IHD发病率比为0.95（95%CI 0.85至1.06），大于48小时的WWH对应的发病率比为1.07（0.94至1.21）。降压药物使用的相应发病率比分别为0.99（0.95至1.04）和1.02（0.97至1.08）。未发现WWH与性别、SES和夜班工作之间存在统计学上的显著交互作用。
在这个丹麦样本中，我们未发现WWH与IHD或降压药物使用之间存在任何统计学上的显著关联。
